Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50001920
TargetAlpha-2A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018739(CHEMBL346492 | 1,3,4,5,6,11b-Hexahydro-2H-11-thia-...)
Affinity DataKi:  4.30nMAssay Description:Affinity to alpha-2 adrenergic receptor by the displacement of [3H]clonidine from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018739(CHEMBL346492 | 1,3,4,5,6,11b-Hexahydro-2H-11-thia-...)
Affinity DataKi:  4.30nMAssay Description:Compound was evaluated for log 1/Ki at alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018739(CHEMBL346492 | 1,3,4,5,6,11b-Hexahydro-2H-11-thia-...)
Affinity DataKi:  16nMAssay Description:Compound was evaluated for log 1/Ki at alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018736(CHEMBL158371 | 1,3,4,5,6,11b-Hexahydro-2H-11-oxa-4...)
Affinity DataKi:  16nMAssay Description:Compound was evaluated for log 1/Ki at alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018739(CHEMBL346492 | 1,3,4,5,6,11b-Hexahydro-2H-11-thia-...)
Affinity DataKi:  16nMAssay Description:Affinity to alpha-1 adrenergic receptor by the displacement of [3H]-prazosin from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018736(CHEMBL158371 | 1,3,4,5,6,11b-Hexahydro-2H-11-oxa-4...)
Affinity DataKi:  16nMAssay Description:Affinity to alpha-2 adrenergic receptor by the displacement of [3H]clonidine from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018737(1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizi...)
Affinity DataKi:  38nMAssay Description:Affinity to alpha-1 adrenergic receptor by the displacement of [3H]-prazosin from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018737(1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizi...)
Affinity DataKi:  38nMAssay Description:Compound was evaluated for log 1/Ki at alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018737(1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizi...)
Affinity DataKi:  60nMAssay Description:Affinity to alpha-2 adrenergic receptor by the displacement of [3H]clonidine from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018737(1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizi...)
Affinity DataKi:  60nMAssay Description:Compound was evaluated for log 1/Ki at alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018736(CHEMBL158371 | 1,3,4,5,6,11b-Hexahydro-2H-11-oxa-4...)
Affinity DataKi:  110nMAssay Description:Compound was evaluated for log 1/Ki at alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018736(CHEMBL158371 | 1,3,4,5,6,11b-Hexahydro-2H-11-oxa-4...)
Affinity DataKi:  110nMAssay Description:Affinity to alpha-1 adrenergic receptor by the displacement of [3H]-prazosin from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018741(CHEMBL346016 | 4,7,8,9,10,10a-Hexahydro-5H-thieno[...)
Affinity DataKi:  195nMAssay Description:Affinity to alpha-2 adrenergic receptor by the displacement of [3H]clonidine from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018741(CHEMBL346016 | 4,7,8,9,10,10a-Hexahydro-5H-thieno[...)
Affinity DataKi:  195nMAssay Description:Compound was evaluated for log 1/Ki at alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018740(CHEMBL160388 | 4,7,8,9,10,10a-Hexahydro-5H-thiazol...)
Affinity DataKi:  347nMAssay Description:Compound was evaluated for log 1/Ki at alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018740(CHEMBL160388 | 4,7,8,9,10,10a-Hexahydro-5H-thiazol...)
Affinity DataKi:  350nMAssay Description:Affinity to alpha-2 adrenergic receptor by the displacement of [3H]clonidine from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018738(CHEMBL345621 | 1,2,3,4,5,6,11,11b-Octahydro-4a,10,...)
Affinity DataKi:  537nMAssay Description:Compound was evaluated for log 1/Ki at alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018738(CHEMBL345621 | 1,2,3,4,5,6,11,11b-Octahydro-4a,10,...)
Affinity DataKi:  540nMAssay Description:Affinity to alpha-1 adrenergic receptor by the displacement of [3H]-prazosin from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018738(CHEMBL345621 | 1,2,3,4,5,6,11,11b-Octahydro-4a,10,...)
Affinity DataKi:  660nMAssay Description:Affinity to alpha-2 adrenergic receptor by the displacement of [3H]clonidine from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018738(CHEMBL345621 | 1,2,3,4,5,6,11,11b-Octahydro-4a,10,...)
Affinity DataKi:  661nMAssay Description:Compound was evaluated for log 1/Ki at alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018741(CHEMBL346016 | 4,7,8,9,10,10a-Hexahydro-5H-thieno[...)
Affinity DataKi:  1.10E+3nMAssay Description:Compound was evaluated for log 1/Ki at alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018741(CHEMBL346016 | 4,7,8,9,10,10a-Hexahydro-5H-thieno[...)
Affinity DataKi:  1.10E+3nMAssay Description:Affinity to alpha-1 adrenergic receptor by the displacement of [3H]-prazosin from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018735(CHEMBL348538 | 5,6,7,8,9,10-Hexahydro-4bH-4,8a-dia...)
Affinity DataKi:  2.00E+3nMAssay Description:Compound was evaluated for log 1/Ki at alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018735(CHEMBL348538 | 5,6,7,8,9,10-Hexahydro-4bH-4,8a-dia...)
Affinity DataKi:  2.00E+3nMAssay Description:Affinity to alpha-2 adrenergic receptor by the displacement of [3H]clonidine from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018740(CHEMBL160388 | 4,7,8,9,10,10a-Hexahydro-5H-thiazol...)
Affinity DataKi:  2.80E+3nMAssay Description:Affinity to alpha-1 adrenergic receptor by the displacement of [3H]-prazosin from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018740(CHEMBL160388 | 4,7,8,9,10,10a-Hexahydro-5H-thiazol...)
Affinity DataKi:  2.82E+3nMAssay Description:Compound was evaluated for log 1/Ki at alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018735(CHEMBL348538 | 5,6,7,8,9,10-Hexahydro-4bH-4,8a-dia...)
Affinity DataKi:  3.24E+3nMAssay Description:Compound was evaluated for log 1/Ki at alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018735(CHEMBL348538 | 5,6,7,8,9,10-Hexahydro-4bH-4,8a-dia...)
Affinity DataKi:  3.25E+3nMAssay Description:Affinity to alpha-1 adrenergic receptor by the displacement of [3H]-prazosin from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018734(CHEMBL156283 | 1,4,5,7,8,9,10,10a-Octahydro-pyrazo...)
Affinity DataKi:  9.55E+3nMAssay Description:Compound was evaluated for log 1/Ki at alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018734(CHEMBL156283 | 1,4,5,7,8,9,10,10a-Octahydro-pyrazo...)
Affinity DataKi:  9.60E+3nMAssay Description:Affinity to alpha-2 adrenergic receptor by the displacement of [3H]clonidine from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018734(CHEMBL156283 | 1,4,5,7,8,9,10,10a-Octahydro-pyrazo...)
Affinity DataKi:  2.40E+4nMAssay Description:Compound was evaluated for log 1/Ki at alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018734(CHEMBL156283 | 1,4,5,7,8,9,10,10a-Octahydro-pyrazo...)
Affinity DataKi:  2.40E+4nMAssay Description:Affinity to alpha-1 adrenergic receptor by the displacement of [3H]-prazosin from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed