BindingDB PrimarySearch_ki

Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50049106

Solute carrier family 22 member 12(Human)
Wuxi Apptec

Curated by ChEMBL

PNG

BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)

IC50: 7.30E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric ac...More data for this Ligand-Target Pair

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3D Structure (crystal)

Solute carrier family 22 member 12(Human)
Wuxi Apptec

Curated by ChEMBL

PNG

BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)

IC50: 7.30E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric ac...More data for this Ligand-Target Pair

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3D Structure (crystal)

Solute carrier family 22 member 12(Human)
Wuxi Apptec

Curated by ChEMBL

PNG

BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)

IC50: 1.51E+4nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric ac...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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3D Structure (crystal)

Cytochrome P450 1A2(Human)
Wuxi Apptec

Curated by ChEMBL

PNG

BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)

IC50: 1.73E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Cytochrome P450 1A2(Human)
Wuxi Apptec

Curated by ChEMBL

PNG

BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)

IC50: 1.73E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Potassium voltage-gated channel subfamily H member 2(Human)
Wuxi Apptec

Curated by ChEMBL

PNG

BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)

IC50: >3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Potassium voltage-gated channel subfamily H member 2(Human)
Wuxi Apptec

Curated by ChEMBL

PNG

BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)

IC50: >3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Potassium voltage-gated channel subfamily H member 2(Human)
Wuxi Apptec

Curated by ChEMBL

PNG

BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)

IC50: >3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Cytochrome P450 2D6(Human)
Wuxi Apptec

Curated by ChEMBL

PNG

BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)

IC50: 3.26E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway
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Cytochrome P450 2D6(Human)
Wuxi Apptec

Curated by ChEMBL

PNG

BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)

IC50: 3.26E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway
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Cytochrome P450 1A2(Human)
Wuxi Apptec

Curated by ChEMBL

PNG

BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)

IC50: 3.93E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair

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Cytochrome P450 2C19(Human)
Wuxi Apptec

Curated by ChEMBL

PNG

BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)

IC50: 6.17E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair

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Cytochrome P450 2C19(Human)
Wuxi Apptec

Curated by ChEMBL

PNG

BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)

IC50: 6.17E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Cytochrome P450 2C19(Human)
Wuxi Apptec

Curated by ChEMBL

PNG

BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)

IC50: 6.17E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Cytochrome P450 3A4(Human)
Wuxi Apptec

Curated by ChEMBL

PNG

BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)

IC50: 7.44E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Cytochrome P450 3A4(Human)
Wuxi Apptec

Curated by ChEMBL

PNG

BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)

IC50: 7.44E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Cytochrome P450 3A4(Human)
Wuxi Apptec

Curated by ChEMBL

PNG

BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)

IC50: 7.44E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair

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Cytochrome P450 2C9(Human)
Wuxi Apptec

Curated by ChEMBL

PNG

BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)

IC50: 7.87E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Cytochrome P450 2C9(Human)
Wuxi Apptec

Curated by ChEMBL

PNG

BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)

IC50: 7.87E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair

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Cytochrome P450 2D6(Human)
Wuxi Apptec

Curated by ChEMBL

PNG

BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)

IC50: >1.00E+5nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway
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Cytochrome P450 2C9(Human)
Wuxi Apptec

Curated by ChEMBL

PNG

BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)

IC50: >1.00E+5nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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