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Found 9 Enz. Inhib. hit(s) with all data for entry = 50000074
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM22984((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated kinetoplast DNA decatenation after 60 mins by ethidium bromide staining based agarose gel electroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50240132(CHEMBL4090898)
Affinity DataIC50:  4.88E+3nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated kinetoplast DNA decatenation after 60 mins by ethidium bromide staining based agarose gel electroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50240135(CHEMBL4066762)
Affinity DataIC50:  5.44E+3nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated kinetoplast DNA decatenation after 60 mins by ethidium bromide staining based agarose gel electroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50240137(CHEMBL4062965)
Affinity DataIC50:  7.08E+3nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated kinetoplast DNA decatenation after 60 mins by ethidium bromide staining based agarose gel electroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50240136(CHEMBL4064044)
Affinity DataIC50:  1.34E+4nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated kinetoplast DNA decatenation after 60 mins by ethidium bromide staining based agarose gel electroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50240138(CHEMBL4093358)
Affinity DataIC50:  2.91E+4nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated kinetoplast DNA decatenation after 60 mins by ethidium bromide staining based agarose gel electroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50240134(CHEMBL4094285)
Affinity DataIC50:  5.29E+4nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated kinetoplast DNA decatenation after 60 mins by ethidium bromide staining based agarose gel electroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50031046(CHEMBL127717 | Indeno[1,2-c]cinnolin-11-one)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated kinetoplast DNA decatenation after 60 mins by ethidium bromide staining based agarose gel electroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50240133(CHEMBL4082118)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated kinetoplast DNA decatenation after 60 mins by ethidium bromide staining based agarose gel electroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed