Compile Data Set for Download or QSAR
maximum 50k data
Found 19 Enz. Inhib. hit(s) with all data for entry = 50000080
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.210nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50006990(CHEMBL299499 | N-Adamantan-1-yl-N'-(4-iodo-phenyl)...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50240232(CHEMBL4080735)
Affinity DataKi:  3nMAssay Description:Displacement of [125I]-IPAG from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50240230(CHEMBL4092687)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50240229(CHEMBL4084182)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50240234(CHEMBL4065001)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50240231(CHEMBL4098778)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50240233(CHEMBL4102152)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [125I]-IPAG from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50240231(CHEMBL4098778)
Affinity DataIC50:  109nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50240229(CHEMBL4084182)
Affinity DataIC50:  216nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50240230(CHEMBL4092687)
Affinity DataIC50:  417nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50240229(CHEMBL4084182)
Affinity DataIC50:  430nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50006990(CHEMBL299499 | N-Adamantan-1-yl-N'-(4-iodo-phenyl)...)
Affinity DataIC50:  491nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50006990(CHEMBL299499 | N-Adamantan-1-yl-N'-(4-iodo-phenyl)...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50425732(ENZALUTAMIDE | US10053433, FC 4.129 | US10806720, ...)
Affinity DataEC50:  420nMAssay Description:Antagonist activity at full length human androgen receptor expressed in mammalian expression system measured after 22 to 24 hrs by luciferase reporte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAndrogen receptor(Homo sapiens (Human))
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50407398(ABIRATERONE ACETATE | CB7630 | Zytiga)
Affinity DataEC50:  1.71E+4nMAssay Description:Antagonist activity at full length human androgen receptor expressed in mammalian expression system measured after 22 to 24 hrs by luciferase reporte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50240229(CHEMBL4084182)
Affinity DataEC50:  1.27E+4nMAssay Description:Antagonist activity at full length human androgen receptor expressed in mammalian expression system measured after 22 to 24 hrs by luciferase reporte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50006990(CHEMBL299499 | N-Adamantan-1-yl-N'-(4-iodo-phenyl)...)
Affinity DataEC50:  9.50E+3nMAssay Description:Antagonist activity at full length human androgen receptor expressed in mammalian expression system measured after 22 to 24 hrs by luciferase reporte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50240230(CHEMBL4092687)
Affinity DataEC50:  2.81E+4nMAssay Description:Antagonist activity at full length human androgen receptor expressed in mammalian expression system measured after 22 to 24 hrs by luciferase reporte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed