Compile Data Set for Download or QSAR
maximum 50k data
Found 60 Enz. Inhib. hit(s) with all data for entry = 50000491
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50175277(CHEMBL3809675)
Affinity DataKi:  40nMAssay Description:Inhibition of recombinant human SphK1 expressed in baculovirus infected sf9 cells using D-erythro-sphingosine as substrate in presence of [gamma-33P]...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM174110((S)-2-(3-(4-octylphenyl)-1,2,4- oxadiazol-5-yl)aze...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of recombinant human SphK2 expressed in baculovirus infected sf9 cells using D-erythro-sphingosine as substrate after 20 mins in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM174110((S)-2-(3-(4-octylphenyl)-1,2,4- oxadiazol-5-yl)aze...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human SphK1 expressed in baculovirus infected sf9 cells using D-erythro-sphingosine as substrate after 20 mins in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Mus musculus (Mouse))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50175277(CHEMBL3809675)
Affinity DataKi:  1.41E+4nMAssay Description:Inhibition of recombinant mouse SphK2 expressed in baculovirus infected sf9 cells using D-erythro-sphingosine as substrate in presence of [gamma-33P]...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50041978(CHEMBL3134157)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of recombinant C-terminal His6-tagged human SphK1 expressed in baculovirus infected sf21 cells using FITC-sphingosine as substrate after 1...More data for this Ligand-Target Pair
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251418(CHEMBL4075031)
Affinity DataIC50:  220nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK1 (1 to 384 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251418(CHEMBL4075031)
Affinity DataIC50:  240nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK2 (1 to 618 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50041978(CHEMBL3134157)
Affinity DataIC50:  360nMAssay Description:Inhibition of human recombinant C-terminal His6 tagged SphK2 expressed in baculovirus infected sf21 cells using FITC-sphingosine as substrate after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251433(CHEMBL4076550)
Affinity DataIC50:  380nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK1 (1 to 384 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251435(CHEMBL4081791)
Affinity DataIC50:  420nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK1 (1 to 384 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251419(CHEMBL4101713)
Affinity DataIC50:  460nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK2 (1 to 618 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251403(CHEMBL4098301)
Affinity DataIC50:  560nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK2 (1 to 618 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251394(CHEMBL1819205)
Affinity DataIC50:  600nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK2 (1 to 618 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251419(CHEMBL4101713)
Affinity DataIC50:  670nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK1 (1 to 384 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251435(CHEMBL4081791)
Affinity DataIC50:  670nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK2 (1 to 618 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251434(CHEMBL4067667)
Affinity DataIC50:  710nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK1 (1 to 384 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251433(CHEMBL4076550)
Affinity DataIC50:  780nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK2 (1 to 618 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251394(CHEMBL1819205)
Affinity DataIC50:  820nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK1 (1 to 384 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251434(CHEMBL4067667)
Affinity DataIC50:  840nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK2 (1 to 618 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251408(CHEMBL4059874)
Affinity DataIC50:  880nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK1 (1 to 384 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251430(CHEMBL4079512)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK1 (1 to 384 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251423(CHEMBL4095076)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK2 (1 to 618 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251403(CHEMBL4098301)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK1 (1 to 384 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251401(CHEMBL4090570)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK2 (1 to 618 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251430(CHEMBL4079512)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK2 (1 to 618 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50600(MLS001029919 | N-(3-Chloro-1,4-dioxo-1,4-dihydro-n...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant human SphK1 using NBD-sphingosine as substrate after 2 hrs in presence of ATP by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251432(CHEMBL4062604)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK2 (1 to 618 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251400(CHEMBL4078892)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK2 (1 to 618 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251423(CHEMBL4095076)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK1 (1 to 384 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251380(CHEMBL4097546)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK1 (1 to 384 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251424(CHEMBL4102840)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK2 (1 to 618 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251431(CHEMBL4105246)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK1 (1 to 384 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50017016(CHEMBL3287036)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of human SphK2 using sphingosine as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251402(CHEMBL4071253)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK2 (1 to 618 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251380(CHEMBL4097546)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK2 (1 to 618 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251424(CHEMBL4102840)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK1 (1 to 384 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50017016(CHEMBL3287036)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human SphK1 using sphingosine as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251401(CHEMBL4090570)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK1 (1 to 384 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251432(CHEMBL4062604)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK1 (1 to 384 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50240721((E)-(2S,3R)-2-Dimethylamino-octadec-4-ene-1,3-diol...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of recombinant human SphK2 using NBD-sphingosine as substrate after 2 hrs in presence of ATP by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50312869(4-(4-(4-chlorophenyl)thiazol-2-ylamino)phenol | CH...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of recombinant human SphK2 using NBD-sphingosine as substrate after 2 hrs in presence of ATP by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251408(CHEMBL4059874)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK2 (1 to 618 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50393641(CHEMBL2158686)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of human SphK2 using sphingosine as substrate after 15 to 20 mins in presence of [gamma-32P]ATP by Cerenkov counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251426(CHEMBL4078560)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK1 (1 to 384 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251409(CHEMBL4089663)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK1 (1 to 384 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251402(CHEMBL4071253)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK1 (1 to 384 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251400(CHEMBL4078892)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK1 (1 to 384 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251395(CHEMBL4103173)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK1 (1 to 384 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251431(CHEMBL4105246)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK2 (1 to 618 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50251381(CHEMBL4087389)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human SphK2 (1 to 618 residues) expressed in baculovirus expression system using sphingosine as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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