Compile Data Set for Download or QSAR
Report error Found 123 Enz. Inhib. hit(s) with all data for entry = 50000401
LigandChemical structure of BindingDB Monomer ID 50249205BDBM50249205(CHEMBL4062753)
Affinity DataIC50: 4nMAssay Description:Inhibition of human ROMK expressed in CHO cells at -70 mV holding potential after 6 mins by whole cell patch clamp Qpatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249244BDBM50249244(CHEMBL4103004)
Affinity DataIC50: 5nMAssay Description:Inhibition of human ROMK expressed in CHO cells at -70 mV holding potential after 6 mins by whole cell patch clamp Qpatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249227BDBM50249227(CHEMBL4095422)
Affinity DataIC50: 8nMAssay Description:Inhibition of human ROMK expressed in CHO cells at -70 mV holding potential after 6 mins by whole cell patch clamp Qpatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249205BDBM50249205(CHEMBL4062753)
Affinity DataIC50: 8nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249299BDBM50249299(CHEMBL4093627)
Affinity DataIC50: 9.5nMAssay Description:Displacement of [35S]MK499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249241BDBM50249241(CHEMBL4092262)
Affinity DataIC50: 11nMAssay Description:Inhibition of human ROMK expressed in CHO cells at -70 mV holding potential after 6 mins by whole cell patch clamp Qpatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249216BDBM50249216(CHEMBL4075906)
Affinity DataIC50: 12nMAssay Description:Inhibition of human ROMK expressed in CHO cells at -70 mV holding potential after 6 mins by whole cell patch clamp Qpatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249244BDBM50249244(CHEMBL4103004)
Affinity DataIC50: 14nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249228BDBM50249228(CHEMBL4075319)
Affinity DataIC50: 17nMAssay Description:Inhibition of human ROMK expressed in CHO cells at -70 mV holding potential after 6 mins by whole cell patch clamp Qpatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249183BDBM50249183(CHEMBL4069245)
Affinity DataIC50: 17nMAssay Description:Inhibition of human ROMK expressed in CHO cells at -70 mV holding potential after 6 mins by whole cell patch clamp Qpatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249216BDBM50249216(CHEMBL4075906)
Affinity DataIC50: 18nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249218BDBM50249218(CHEMBL4086822)
Affinity DataIC50: 20nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249228BDBM50249228(CHEMBL4075319)
Affinity DataIC50: 23nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249202BDBM50249202(CHEMBL4059846)
Affinity DataIC50: 27nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50235200BDBM50235200(CHEMBL4098260)
Affinity DataIC50: 29nMAssay Description:Inhibition of human ROMK expressed in CHO cells at -70 mV holding potential after 6 mins by whole cell patch clamp Qpatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249183BDBM50249183(CHEMBL4069245)
Affinity DataIC50: 35nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249227BDBM50249227(CHEMBL4095422)
Affinity DataIC50: 37nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 338476BDBM338476(US9751881, Example 8)
Affinity DataIC50: 37nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249183BDBM50249183(CHEMBL4069245)
Affinity DataIC50: 38nMAssay Description:Inhibition of rat ROMK expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249249BDBM50249249(CHEMBL4071141)
Affinity DataIC50: 41nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50235200BDBM50235200(CHEMBL4098260)
Affinity DataIC50: 41nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249187BDBM50249187(CHEMBL4075415)
Affinity DataIC50: 42nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249219BDBM50249219(CHEMBL4076563)
Affinity DataIC50: 47nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249315BDBM50249315(CHEMBL4075868)
Affinity DataIC50: 51nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249217BDBM50249217(CHEMBL4072929)
Affinity DataIC50: 54nMAssay Description:Displacement of [35S]MK499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249305BDBM50249305(CHEMBL4071329)
Affinity DataIC50: 54nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249281BDBM50249281(CHEMBL4071345)
Affinity DataIC50: 56nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249246BDBM50249246(CHEMBL4078730)
Affinity DataIC50: 59nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249241BDBM50249241(CHEMBL4092262)
Affinity DataIC50: 64nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249206BDBM50249206(CHEMBL4067649)
Affinity DataIC50: 65nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249272BDBM50249272(CHEMBL4082637)
Affinity DataIC50: 68nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249274BDBM50249274(CHEMBL4093121)
Affinity DataIC50: 77nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249163BDBM50249163(CHEMBL4062796)
Affinity DataIC50: 88nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249273BDBM50249273(CHEMBL4059965)
Affinity DataIC50: 95nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249242BDBM50249242(CHEMBL4086697)
Affinity DataIC50: 120nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249282BDBM50249282(CHEMBL4070003)
Affinity DataIC50: 130nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249250BDBM50249250(CHEMBL4070542)
Affinity DataIC50: 130nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249248BDBM50249248(CHEMBL4075427)
Affinity DataIC50: 180nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249280BDBM50249280(CHEMBL4071603)
Affinity DataIC50: 190nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249157BDBM50249157(CHEMBL4071221)
Affinity DataIC50: 250nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249189BDBM50249189(CHEMBL4071084)
Affinity DataIC50: 260nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249271BDBM50249271(CHEMBL4084167)
Affinity DataIC50: 270nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249299BDBM50249299(CHEMBL4093627)
Affinity DataIC50: 340nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249308BDBM50249308(CHEMBL4075425)
Affinity DataIC50: 350nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249306BDBM50249306(CHEMBL4081764)
Affinity DataIC50: 420nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249275BDBM50249275(CHEMBL4078280)
Affinity DataIC50: 420nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249251BDBM50249251(CHEMBL4061173)
Affinity DataIC50: 430nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249243BDBM50249243(CHEMBL4072014)
Affinity DataIC50: 430nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249307BDBM50249307(CHEMBL4093837)
Affinity DataIC50: 490nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50249217BDBM50249217(CHEMBL4072929)
Affinity DataIC50: 510nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
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