Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50049002
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: 66nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: 83nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232679(CHEMBL4068784 | US11358936, Compound 4-5)
Affinity DataIC50: 126nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Rat)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: 127nMAssay Description:Inhibition of full length recombinant rat LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Mouse)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: 128nMAssay Description:Inhibition of full length recombinant mouse LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Rat)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232679(CHEMBL4068784 | US11358936, Compound 4-5)
Affinity DataIC50: 136nMAssay Description:Inhibition of full length recombinant rat LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232679(CHEMBL4068784 | US11358936, Compound 4-5)
Affinity DataIC50: 190nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232681(CHEMBL4099444 | US11358936, Compound 4-11)
Affinity DataIC50: 203nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232679(CHEMBL4068784 | US11358936, Compound 4-5)
Affinity DataIC50: 214nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged LOXL3 (1 to 753 residues) assessed as reduction in H2O2 production using DAP as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Mouse)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232679(CHEMBL4068784 | US11358936, Compound 4-5)
Affinity DataIC50: 227nMAssay Description:Inhibition of full length recombinant mouse LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: 243nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232682(CHEMBL3467241 | US11358936, Compound 2-7)
Affinity DataIC50: 309nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232693(CHEMBL4072524 | US11358936, Compound 2-3)
Affinity DataIC50: 321nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232684(CHEMBL4103840 | US11358936, Compound 4-3)
Affinity DataIC50: 385nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: 396nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells spiked into human whole blood assessed as reduction in H2O2 production using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232694(CHEMBL4079586 | US11358936, Compound 4-2)
Affinity DataIC50: 431nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetProtein-lysine 6-oxidase(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: 550nMAssay Description:Inhibition of full length recombinant human LOX expressed in HEK cells assessed as reduction in H2O2 production using DAP as substrate preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232691(CHEMBL4068773)
Affinity DataIC50: 670nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232698(CHEMBL1235374 | EN300-50211)
Affinity DataIC50: 719nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232688(CHEMBL4075843)
Affinity DataIC50: 902nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232685(CHEMBL4096085 | US11358936, Compound 4-4)
Affinity DataIC50: 999nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232690(4-Aminomethyl-Benzamidine | CHEMBL187301)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232683(CHEMBL4066086)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232687(CHEMBL1188378)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232679(CHEMBL4068784 | US11358936, Compound 4-5)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells spiked into human whole blood assessed as reduction in H2O2 production using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232697((3-(Methoxycarbonyl)Phenyl)Methanaminium | CHEMBL1...)
Affinity DataIC50: 3.54E+3nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50408793(CHEMBL148986)
Affinity DataIC50: 3.62E+3nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232689(CHEMBL4098510)
Affinity DataIC50: 4.97E+3nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetProtein-lysine 6-oxidase(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232679(CHEMBL4068784 | US11358936, Compound 4-5)
Affinity DataIC50: 5.91E+3nMAssay Description:Inhibition of full length recombinant human LOX expressed in HEK cells assessed as reduction in H2O2 production using DAP as substrate preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232695(CHEMBL4060123)
Affinity DataIC50: 6.04E+3nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232686(CHEMBL4088360)
Affinity DataIC50: 8.21E+3nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50113835(Integrase inhibitor, R1{2} | CHEMBL12392 | 4-fluor...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232679(CHEMBL4068784 | US11358936, Compound 4-5)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232679(CHEMBL4068784 | US11358936, Compound 4-5)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232679(CHEMBL4068784 | US11358936, Compound 4-5)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232680(CHEMBL4084804)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232692(CHEMBL4098672)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50408786(CHEMBL148476)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM10758(14C-phenylethylamine | 2-phenylethan-1-amine | CHE...)
Affinity DataIC50: 6.01E+4nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM10999(CHEMBL522 | Benzenemethanamine | phenylmethanamine...)
Affinity DataIC50: 6.47E+4nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50113851(Tranylcypromine,(+) | TRANYLCYPROMINE | US8609708,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232696(CHEMBL4084448)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed