Compile Data Set for Download or QSAR
Report error Found 85 Enz. Inhib. hit(s) with all data for entry = 50000207
LigandChemical structure of BindingDB Monomer ID 50242470BDBM50242470(CHEMBL4079058)
Affinity DataIC50: 70nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242456BDBM50242456(CHEMBL4104533)
Affinity DataIC50: 113nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242485BDBM50242485(CHEMBL4093738)
Affinity DataIC50: 210nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242463BDBM50242463(CHEMBL4080310)
Affinity DataIC50: 215nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242481BDBM50242481(CHEMBL4103215)
Affinity DataIC50: 218nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242462BDBM50242462(CHEMBL4085721)
Affinity DataIC50: 607nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50242459BDBM50242459(CHEMBL4085168)
Affinity DataIC50: 662nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242484BDBM50242484(CHEMBL4095893)
Affinity DataIC50: 880nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242488BDBM50242488(CHEMBL4062215)
Affinity DataIC50: 960nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242432BDBM50242432(CHEMBL4099806)
Affinity DataIC50: 961nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242460BDBM50242460(CHEMBL4101460)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242487BDBM50242487(CHEMBL4085857)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242472BDBM50242472(CHEMBL4101337)
Affinity DataIC50: 2.11E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242431BDBM50242431(CHEMBL4072919)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242473BDBM50242473(CHEMBL4077865)
Affinity DataIC50: 2.55E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242465BDBM50242465(CHEMBL4083468)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50241844BDBM50241844(CHEMBL4097075)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242453BDBM50242453(CHEMBL4078944)
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242471BDBM50242471(CHEMBL4094523)
Affinity DataIC50: 3.94E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242464BDBM50242464(CHEMBL4085988)
Affinity DataIC50: 4.39E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242467BDBM50242467(CHEMBL4086795)
Affinity DataIC50: 7.31E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242461BDBM50242461(CHEMBL4102371)
Affinity DataIC50: 8.83E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242498BDBM50242498(CHEMBL4097229)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242483BDBM50242483(CHEMBL4103653)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242465BDBM50242465(CHEMBL4083468)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242489BDBM50242489(CHEMBL4064456)
Affinity DataIC50: 9.09E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242486BDBM50242486(CHEMBL4065364)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242466BDBM50242466(CHEMBL4074640)
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242479BDBM50242479(CHEMBL4103855)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242430BDBM50242430(CHEMBL4066024)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242462BDBM50242462(CHEMBL4085721)
Affinity DataIC50: 2.07E+4nMAssay Description:Inhibition of TrkC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242454BDBM50242454(CHEMBL4093603)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242444BDBM50242444(CHEMBL4104935)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242487BDBM50242487(CHEMBL4085857)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242483BDBM50242483(CHEMBL4103653)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242468BDBM50242468(CHEMBL4078099)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242500BDBM50242500(CHEMBL4084906)
Affinity DataIC50: 3.09E+4nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242468BDBM50242468(CHEMBL4078099)
Affinity DataIC50: 3.66E+4nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242467BDBM50242467(CHEMBL4086795)
Affinity DataIC50: 3.85E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242490BDBM50242490(CHEMBL4090227)
Affinity DataIC50: 3.86E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242445BDBM50242445(CHEMBL4100610)
Affinity DataIC50: 4.73E+4nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242459BDBM50242459(CHEMBL4085168)
Affinity DataIC50: 4.79E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50241257BDBM50241257(CHEMBL4073976)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242430BDBM50242430(CHEMBL4066024)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242472BDBM50242472(CHEMBL4101337)
Affinity DataIC50: 5.35E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242461BDBM50242461(CHEMBL4102371)
Affinity DataIC50: 5.84E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242499BDBM50242499(CHEMBL4080705)
Affinity DataIC50: 6.43E+4nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242463BDBM50242463(CHEMBL4080310)
Affinity DataIC50: 6.82E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242456BDBM50242456(CHEMBL4104533)
Affinity DataIC50: 6.88E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242471BDBM50242471(CHEMBL4094523)
Affinity DataIC50: 7.02E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
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