Compile Data Set for Download or QSAR
maximum 50k data
Found 85 Enz. Inhib. hit(s) with all data for entry = 50000207
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242470(CHEMBL4079058)
Affinity DataIC50:  70nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242456(CHEMBL4104533)
Affinity DataIC50:  113nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242485(CHEMBL4093738)
Affinity DataIC50:  210nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242463(CHEMBL4080310)
Affinity DataIC50:  215nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242481(CHEMBL4103215)
Affinity DataIC50:  218nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242462(CHEMBL4085721)
Affinity DataIC50:  607nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242459(CHEMBL4085168)
Affinity DataIC50:  662nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242484(CHEMBL4095893)
Affinity DataIC50:  880nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242488(CHEMBL4062215)
Affinity DataIC50:  960nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242432(CHEMBL4099806)
Affinity DataIC50:  961nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242460(CHEMBL4101460)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242487(CHEMBL4085857)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242472(CHEMBL4101337)
Affinity DataIC50:  2.11E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242431(CHEMBL4072919)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242473(CHEMBL4077865)
Affinity DataIC50:  2.55E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242465(CHEMBL4083468)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50241844(CHEMBL4097075)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242453(CHEMBL4078944)
Affinity DataIC50:  3.39E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242471(CHEMBL4094523)
Affinity DataIC50:  3.94E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242464(CHEMBL4085988)
Affinity DataIC50:  4.39E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242467(CHEMBL4086795)
Affinity DataIC50:  7.31E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242461(CHEMBL4102371)
Affinity DataIC50:  8.83E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242483(CHEMBL4103653)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242498(CHEMBL4097229)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242465(CHEMBL4083468)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242489(CHEMBL4064456)
Affinity DataIC50:  9.09E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242486(CHEMBL4065364)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242466(CHEMBL4074640)
Affinity DataIC50:  1.19E+4nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242479(CHEMBL4103855)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242430(CHEMBL4066024)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242462(CHEMBL4085721)
Affinity DataIC50:  2.07E+4nMAssay Description:Inhibition of TrkC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242454(CHEMBL4093603)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242444(CHEMBL4104935)
Affinity DataIC50:  2.51E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242487(CHEMBL4085857)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242468(CHEMBL4078099)
Affinity DataIC50: >2.70E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242483(CHEMBL4103653)
Affinity DataIC50: >2.70E+4nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242500(CHEMBL4084906)
Affinity DataIC50:  3.09E+4nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242468(CHEMBL4078099)
Affinity DataIC50:  3.66E+4nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242467(CHEMBL4086795)
Affinity DataIC50:  3.85E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242490(CHEMBL4090227)
Affinity DataIC50:  3.86E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242445(CHEMBL4100610)
Affinity DataIC50:  4.73E+4nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242459(CHEMBL4085168)
Affinity DataIC50:  4.79E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50241257(CHEMBL4073976)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242430(CHEMBL4066024)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242472(CHEMBL4101337)
Affinity DataIC50:  5.35E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242461(CHEMBL4102371)
Affinity DataIC50:  5.84E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242499(CHEMBL4080705)
Affinity DataIC50:  6.43E+4nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242463(CHEMBL4080310)
Affinity DataIC50:  6.82E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242456(CHEMBL4104533)
Affinity DataIC50:  6.88E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242471(CHEMBL4094523)
Affinity DataIC50:  7.02E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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