Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50022532
LigandPNGBDBM50255583(CHEMBL4096813)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of N-terminal His-tagged full-length recombinant human MTH1 (1 to 156 residues) expressed in Escherichia coli using 8-oxo-dGTP as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50152124(CHEMBL3782004)
Affinity DataEC50:  7.60nMAssay Description:Binding affinity to MTH1 in human K562 cells assessed as increase in thermal stabilization by measuring change in melting temperature at 55 degreeC i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50152124(CHEMBL3782004)
Affinity DataIC50: 12nMAssay Description:Inhibition of N-terminal His-tagged full-length recombinant human MTH1 (1 to 156 residues) expressed in Escherichia coli using 8-oxo-dGTP as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed