Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50022532
Affinity DataIC50: 2.30nMAssay Description:Inhibition of N-terminal His-tagged full-length recombinant human MTH1 (1 to 156 residues) expressed in Escherichia coli using 8-oxo-dGTP as substrat...More data for this Ligand-Target Pair
Affinity DataEC50: 7.60nMAssay Description:Binding affinity to MTH1 in human K562 cells assessed as increase in thermal stabilization by measuring change in melting temperature at 55 degreeC i...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of N-terminal His-tagged full-length recombinant human MTH1 (1 to 156 residues) expressed in Escherichia coli using 8-oxo-dGTP as substrat...More data for this Ligand-Target Pair

3D Structure (crystal)