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Found 9 Enz. Inhib. hit(s) with all data for entry = 50001095
TargetTrypanothione reductase(Trypanosoma cruzi)
Julius-Maximilians-University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM10469(Bis-THA inhibitor 1c | Bis-THA inhibitor 8 | CHEMB...)
Affinity DataKi:  400nMAssay Description:Competitive inhibition of Trypanosoma cruzi trypanothione reductase using varying levels of trypanothione disulfide as substrate by Lineweaver--burk ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Julius-Maximilians-University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50269328(CHEMBL3814557)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 10 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Julius-Maximilians-University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM9053(6-chloro-N-{6-[(6-chloro-1,2,3,4-tetrahydroacridin...)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 10 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Julius-Maximilians-University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50269330(CHEMBL3814548)
Affinity DataIC50:  1.33E+4nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 10 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Julius-Maximilians-University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM8964(CHEMBL75274 | Homodimeric Tacrine Analog 3c | N-[8...)
Affinity DataIC50:  1.69E+4nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 10 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Julius-Maximilians-University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50269331(CHEMBL3815015)
Affinity DataIC50:  1.81E+4nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 10 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Julius-Maximilians-University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM10469(Bis-THA inhibitor 1c | Bis-THA inhibitor 8 | CHEMB...)
Affinity DataIC50:  1.94E+4nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 10 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Julius-Maximilians-University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50269327(CHEMBL3813885)
Affinity DataIC50:  2.66E+4nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 10 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Julius-Maximilians-University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50269329(CHEMBL4103108)
Affinity DataIC50:  2.66E+4nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 10 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed