Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50001337
TargetProstaglandin G/H synthase 1(Sheep)
Thomas Jefferson University

Curated by ChEMBL
LigandPNGBDBM50376383(CHEMBL259972)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of ovine COX1 catalytic activity using arachidonic acid as substrate preincubated for 5 mins followed by substrate and hemin addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Thomas Jefferson University

Curated by ChEMBL
LigandPNGBDBM50153040(3-(5-Chloro-furan-2-yl)-5-methyl-4-phenyl-isoxazol...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of ovine COX1 catalytic activity using arachidonic acid as substrate preincubated for 5 mins followed by substrate and hemin addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Sheep)
Thomas Jefferson University

Curated by ChEMBL
LigandPNGBDBM50376383(CHEMBL259972)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant ovine COX2 catalytic activity using arachidonic acid as substrate preincubated for 5 mins followed by substrate and hemin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Thomas Jefferson University

Curated by ChEMBL
LigandPNGBDBM50153040(3-(5-Chloro-furan-2-yl)-5-methyl-4-phenyl-isoxazol...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant ovine COX2 catalytic activity using arachidonic acid as substrate preincubated for 5 mins followed by substrate and hemin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed