Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50001100
LigandChemical structure of BindingDB Monomer ID 50243040BDBM50243040(CHEMBL4065068)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to TACE catalytic domain (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269406BDBM50269406(CHEMBL4099646)
Affinity DataIC50: 61nMAssay Description:Inhibition of TACE in human whole blood assessed as inhibition of LPS-stimulated TNFalpha production pretreated for 1 hr followed by LPS stimulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269407BDBM50269407(CHEMBL4099281)
Affinity DataIC50: 92nMAssay Description:Inhibition of TACE in human whole blood assessed as inhibition of LPS-stimulated TNFalpha production pretreated for 1 hr followed by LPS stimulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269399BDBM50269399(CHEMBL4076728)
Affinity DataIC50: 104nMAssay Description:Inhibition of TACE in human whole blood assessed as inhibition of LPS-stimulated TNFalpha production pretreated for 1 hr followed by LPS stimulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269400BDBM50269400(CHEMBL4077272)
Affinity DataIC50: 141nMAssay Description:Inhibition of TACE in human whole blood assessed as inhibition of LPS-stimulated TNFalpha production pretreated for 1 hr followed by LPS stimulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269408BDBM50269408(CHEMBL4102424)
Affinity DataIC50: 156nMAssay Description:Inhibition of TACE in human whole blood assessed as inhibition of LPS-stimulated TNFalpha production pretreated for 1 hr followed by LPS stimulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269404BDBM50269404(CHEMBL4085841)
Affinity DataIC50: 176nMAssay Description:Inhibition of TACE in human whole blood assessed as inhibition of LPS-stimulated TNFalpha production pretreated for 1 hr followed by LPS stimulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269401BDBM50269401(CHEMBL4077298)
Affinity DataIC50: 178nMAssay Description:Inhibition of TACE in human whole blood assessed as inhibition of LPS-stimulated TNFalpha production pretreated for 1 hr followed by LPS stimulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269397BDBM50269397(CHEMBL4074184)
Affinity DataIC50: 281nMAssay Description:Inhibition of TACE in human whole blood assessed as inhibition of LPS-stimulated TNFalpha production pretreated for 1 hr followed by LPS stimulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269402BDBM50269402(CHEMBL4098911)
Affinity DataIC50: 282nMAssay Description:Inhibition of TACE in human whole blood assessed as inhibition of LPS-stimulated TNFalpha production pretreated for 1 hr followed by LPS stimulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50243040BDBM50243040(CHEMBL4065068)
Affinity DataIC50: 287nMAssay Description:Inhibition of TACE in human whole blood assessed as inhibition of LPS-stimulated TNFalpha production pretreated for 1 hr followed by LPS stimulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269403BDBM50269403(CHEMBL4080126)
Affinity DataIC50: 339nMAssay Description:Inhibition of TACE in human whole blood assessed as inhibition of LPS-stimulated TNFalpha production pretreated for 1 hr followed by LPS stimulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269405BDBM50269405(CHEMBL4068636)
Affinity DataIC50: 560nMAssay Description:Inhibition of TACE in human whole blood assessed as inhibition of LPS-stimulated TNFalpha production pretreated for 1 hr followed by LPS stimulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269398BDBM50269398(CHEMBL4089626)
Affinity DataIC50: 7.15E+3nMAssay Description:Inhibition of TACE in human whole blood assessed as inhibition of LPS-stimulated TNFalpha production pretreated for 1 hr followed by LPS stimulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed