Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50003222
TargetEpidermal growth factor receptor(Human)
University of Kwazulu Natal

Curated by ChEMBL
LigandPNGBDBM50468249(CHEMBL4280817)
Affinity DataIC50: 9nMAssay Description:Inhibition of 6x-His-tagged human EGFR cytoplasmic domain (645 to 1186 amino acids) assessed as reduction in autophosphorylation pre-incubated for 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
University of Kwazulu Natal

Curated by ChEMBL
LigandPNGBDBM50468250(CHEMBL4286029)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of VEGFR1 (unknown origin) using KKKSPGEYVNIEFG substrate and [33P-g-ATP] incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
University of Kwazulu Natal

Curated by ChEMBL
LigandPNGBDBM50468251(CHEMBL4287524)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of VEGFR1 (unknown origin) using KKKSPGEYVNIEFG substrate and [33P-g-ATP] incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
University of Kwazulu Natal

Curated by ChEMBL
LigandPNGBDBM153292(3-Benzofuran-2-yl-5-(4-dimethylamino-naphthalen-1-...)
Affinity DataIC50: 4.72E+3nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase pre-incubated for 30 mins before L-DOPA substrate addition and measured after 1 min by spec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
University of Kwazulu Natal

Curated by ChEMBL
LigandPNGBDBM50031467(Kojic Acid | CHEMBL287556 | 5-HYDROXY-2-(HYDROXYME...)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase pre-incubated for 30 mins before L-DOPA substrate addition and measured after 1 min by spec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed