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Report error Found 58 Enz. Inhib. hit(s) with all data for entry = 50000818
TargetSodium-dependent dopamine transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)
Affinity DataIC50:  40nMAssay Description:Inhibition of re-uptake of [3H]-DA at human DAT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50117973(CHEMBL3612829)
Affinity DataIC50:  56nMAssay Description:Inhibition of re-uptake of [3H]-5-HT at human SERT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)
Affinity DataIC50:  110nMAssay Description:Inhibition of re-uptake of [3H]-NE at human NET expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50235734(CHEMBL4083724)
Affinity DataIC50:  159nMAssay Description:Inhibition of re-uptake of [3H]-5-HT at human SERT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)
Affinity DataIC50:  200nMAssay Description:Inhibition of re-uptake of [3H]-5-HT at human SERT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261046(CHEMBL4071385)
Affinity DataIC50:  310nMAssay Description:Inhibition of re-uptake of [3H]-5-HT at human SERT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261040(CHEMBL4099475)
Affinity DataIC50:  540nMAssay Description:Inhibition of re-uptake of [3H]-5-HT at human SERT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50235723(CHEMBL4082902)
Affinity DataIC50:  579nMAssay Description:Inhibition of re-uptake of [3H]-5-HT at human SERT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261032(CHEMBL4061167)
Affinity DataIC50:  880nMAssay Description:Inhibition of re-uptake of [3H]-5-HT at human SERT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50155558(CHEMBL3774957)
Affinity DataIC50:  1.18E+3nMAssay Description:Inhibition of re-uptake of [3H]-5-HT at human SERT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50048392(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of re-uptake of [3H]-DA at human DAT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261044(CHEMBL4068516)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibition of re-uptake of [3H]-5-HT at human SERT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261029(CHEMBL4083969)
Affinity DataIC50:  1.32E+3nMAssay Description:Inhibition of re-uptake of [3H]-5-HT at human SERT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261044(CHEMBL4068516)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of re-uptake of [3H]-NE at human NET expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261039(CHEMBL4101959)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of re-uptake of [3H]-5-HT at human SERT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261044(CHEMBL4068516)
Affinity DataIC50:  1.98E+3nMAssay Description:Inhibition of re-uptake of [3H]-DA at human DAT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261047(CHEMBL4063974)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of re-uptake of [3H]-5-HT at human SERT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261047(CHEMBL4063974)
Affinity DataIC50:  2.28E+3nMAssay Description:Inhibition of re-uptake of [3H]-NE at human NET expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261046(CHEMBL4071385)
Affinity DataIC50:  2.51E+3nMAssay Description:Inhibition of re-uptake of [3H]-NE at human NET expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)
Affinity DataIC50:  2.55E+3nMAssay Description:Inhibition of re-uptake of [3H]-NE at human NET expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261041(CHEMBL4073602)
Affinity DataIC50:  2.58E+3nMAssay Description:Inhibition of re-uptake of [3H]-NE at human NET expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261040(CHEMBL4099475)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of re-uptake of [3H]-NE at human NET expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261032(CHEMBL4061167)
Affinity DataIC50:  3.03E+3nMAssay Description:Inhibition of re-uptake of [3H]-NE at human NET expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261030(CHEMBL4074417)
Affinity DataIC50:  3.08E+3nMAssay Description:Inhibition of re-uptake of [3H]-NE at human NET expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261041(CHEMBL4073602)
Affinity DataIC50:  3.13E+3nMAssay Description:Inhibition of re-uptake of [3H]-5-HT at human SERT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50048392(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Affinity DataIC50:  3.24E+3nMAssay Description:Inhibition of re-uptake of [3H]-NE at human NET expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

TargetSodium-dependent dopamine transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261047(CHEMBL4063974)
Affinity DataIC50:  3.29E+3nMAssay Description:Inhibition of re-uptake of [3H]-DA at human DAT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261043(CHEMBL4060019)
Affinity DataIC50:  3.45E+3nMAssay Description:Inhibition of re-uptake of [3H]-NE at human NET expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261045(CHEMBL4094228)
Affinity DataIC50:  3.46E+3nMAssay Description:Inhibition of re-uptake of [3H]-NE at human NET expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261039(CHEMBL4101959)
Affinity DataIC50:  3.59E+3nMAssay Description:Inhibition of re-uptake of [3H]-NE at human NET expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261033(CHEMBL4083042)
Affinity DataIC50:  3.74E+3nMAssay Description:Inhibition of re-uptake of [3H]-DA at human DAT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261029(CHEMBL4083969)
Affinity DataIC50:  3.96E+3nMAssay Description:Inhibition of re-uptake of [3H]-NE at human NET expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261043(CHEMBL4060019)
Affinity DataIC50:  3.96E+3nMAssay Description:Inhibition of re-uptake of [3H]-5-HT at human SERT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261032(CHEMBL4061167)
Affinity DataIC50:  4.02E+3nMAssay Description:Inhibition of re-uptake of [3H]-DA at human DAT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261038(CHEMBL4091738)
Affinity DataIC50:  4.05E+3nMAssay Description:Inhibition of re-uptake of [3H]-5-HT at human SERT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261030(CHEMBL4074417)
Affinity DataIC50:  4.05E+3nMAssay Description:Inhibition of re-uptake of [3H]-5-HT at human SERT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261042(CHEMBL4081927)
Affinity DataIC50:  4.34E+3nMAssay Description:Inhibition of re-uptake of [3H]-NE at human NET expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261034(CHEMBL4072566)
Affinity DataIC50:  5.02E+3nMAssay Description:Inhibition of re-uptake of [3H]-NE at human NET expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261040(CHEMBL4099475)
Affinity DataIC50:  5.04E+3nMAssay Description:Inhibition of re-uptake of [3H]-DA at human DAT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261033(CHEMBL4083042)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of re-uptake of [3H]-NE at human NET expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261045(CHEMBL4094228)
Affinity DataIC50:  5.13E+3nMAssay Description:Inhibition of re-uptake of [3H]-5-HT at human SERT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261039(CHEMBL4101959)
Affinity DataIC50:  5.18E+3nMAssay Description:Inhibition of re-uptake of [3H]-DA at human DAT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261034(CHEMBL4072566)
Affinity DataIC50:  5.25E+3nMAssay Description:Inhibition of re-uptake of [3H]-5-HT at human SERT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261038(CHEMBL4091738)
Affinity DataIC50:  5.52E+3nMAssay Description:Inhibition of re-uptake of [3H]-NE at human NET expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261046(CHEMBL4071385)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of re-uptake of [3H]-DA at human DAT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261029(CHEMBL4083969)
Affinity DataIC50:  6.55E+3nMAssay Description:Inhibition of re-uptake of [3H]-DA at human DAT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261041(CHEMBL4073602)
Affinity DataIC50:  8.32E+3nMAssay Description:Inhibition of re-uptake of [3H]-DA at human DAT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261033(CHEMBL4083042)
Affinity DataIC50:  8.81E+3nMAssay Description:Inhibition of re-uptake of [3H]-5-HT at human SERT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261031(CHEMBL4095847)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of re-uptake of [3H]-NE at human NET expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50261031(CHEMBL4095847)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of re-uptake of [3H]-DA at human DAT expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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