Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 50035648
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataIC50:  1.60nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
LigandPNGBDBM50019947(CHEMBL299471 | Propionic acid 1-[4-(4-fluoro-pheny...)
Affinity DataIC50:  3nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50019948(CHEMBL292006 | Propionic acid 1-[4-(4-fluoro-pheny...)
Affinity DataIC50:  3.30nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
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Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50:  4.20nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50019946(CHEMBL56547 | Propionic acid 1-[4-(4-fluoro-phenyl...)
Affinity DataIC50:  8.70nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50:  24nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019947(CHEMBL299471 | Propionic acid 1-[4-(4-fluoro-pheny...)
Affinity DataIC50:  29nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019948(CHEMBL292006 | Propionic acid 1-[4-(4-fluoro-pheny...)
Affinity DataIC50:  34nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50:  41nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019946(CHEMBL56547 | Propionic acid 1-[4-(4-fluoro-phenyl...)
Affinity DataIC50:  47nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019949(1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-phenyl-piperidi...)
Affinity DataIC50:  47nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019954(1-(4-Fluoro-phenyl)-4-(4-hydroxy-3-methyl-4-phenyl...)
Affinity DataIC50:  55nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019950(1-(4-Fluoro-phenyl)-4-(4-phenyl-piperidin-1-yl)-bu...)
Affinity DataIC50:  70nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019945(1-(4-Fluoro-phenyl)-4-(4-hydroxy-3-methyl-4-phenyl...)
Affinity DataIC50:  80nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29644((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)
Affinity DataIC50:  302nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50:  550nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50019952(CHEMBL57306 | Propionic acid 1-[4-(4-fluoro-phenyl...)
Affinity DataIC50:  598nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019954(1-(4-Fluoro-phenyl)-4-(4-hydroxy-3-methyl-4-phenyl...)
Affinity DataIC50:  1.65E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019947(CHEMBL299471 | Propionic acid 1-[4-(4-fluoro-pheny...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019948(CHEMBL292006 | Propionic acid 1-[4-(4-fluoro-pheny...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019945(1-(4-Fluoro-phenyl)-4-(4-hydroxy-3-methyl-4-phenyl...)
Affinity DataIC50:  2.65E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019949(1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-phenyl-piperidi...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Affinity DataIC50:  3.05E+3nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019946(CHEMBL56547 | Propionic acid 1-[4-(4-fluoro-phenyl...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50019949(1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-phenyl-piperidi...)
Affinity DataIC50:  3.22E+3nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019953(1-(4-Fluoro-phenyl)-4-(4-hydroxy-piperidin-1-yl)-b...)
Affinity DataIC50: >5.00E+3nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50019953(1-(4-Fluoro-phenyl)-4-(4-hydroxy-piperidin-1-yl)-b...)
Affinity DataIC50:  5.50E+3nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50:  5.69E+3nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(RAT)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019950(1-(4-Fluoro-phenyl)-4-(4-phenyl-piperidin-1-yl)-bu...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50019950(1-(4-Fluoro-phenyl)-4-(4-phenyl-piperidin-1-yl)-bu...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity against HMG-CoA reductase in rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50019945(1-(4-Fluoro-phenyl)-4-(4-hydroxy-3-methyl-4-phenyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50019954(1-(4-Fluoro-phenyl)-4-(4-hydroxy-3-methyl-4-phenyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using the natural substrate partially pure angiotensinogen at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019952(CHEMBL57306 | Propionic acid 1-[4-(4-fluoro-phenyl...)
Affinity DataIC50: >5.00E+4nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed