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Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50000143
TargetTransient receptor potential cation channel subfamily V member 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50241484(CHEMBL4095861)
Affinity DataKi:  0.630nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cell membranes after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50398494(CHEMBL2177429)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]MPOU from human TRPV1 expressed in CHO cell membranes after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50398494(CHEMBL2177429)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cell membranes after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50133817(4-(3-Chloro-pyridin-2-yl)-piperazine-1-carboxylic ...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cell membranes after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Rat)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50241484(CHEMBL4095861)
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]RTX from rat TRPV1 after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM125059(US8765733, 24)
Affinity DataKi:  6.80nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cell membranes after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50133817(4-(3-Chloro-pyridin-2-yl)-piperazine-1-carboxylic ...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]MPOU from human TRPV1 expressed in CHO cell membranes after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM125059(US8765733, 24)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]MPOU from human TRPV1 expressed in CHO cell membranes after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM20461((6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methy...)
Affinity DataKi:  1.14E+3nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cell membranes after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetTransient receptor potential cation channel subfamily V member 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM20461((6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methy...)
Affinity DataKi:  2.53E+3nMAssay Description:Displacement of [3H]MPOU from human TRPV1 expressed in CHO cell membranes after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetTransient receptor potential cation channel subfamily V member 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50241485(CHEMBL4060041)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to human TRPV1 expressed in CHO cells after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM20458(1-[(1R)-5-tert-butyl-2,3-dihydro-1H-inden-1-yl]-3-...)
Affinity DataKd:  3.40nMAssay Description:Displacement of [3H]A-778317 from human TRPV1 expressed in CHO cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Rat)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50241485(CHEMBL4060041)
Affinity DataKd:  0.0640nMAssay Description:Binding affinity to rat TRPV1 after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50241484(CHEMBL4095861)
Affinity DataKd:  0.589nMAssay Description:Binding affinity to human TRPV1 expressed in CHO cells after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50241484(CHEMBL4095861)
Affinity DataKd:  0.590nMAssay Description:Binding affinity to human TRPV1 expressed in CHO cells after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed