Compile Data Set for Download or QSAR
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Found 8 Enz. Inhib. hit(s) with all data for entry = 50000849
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50261767(CHEMBL4061116)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of 3 nM recombinant human topoisomerase-2alpha catalytic activity expressed in Saccharomyces cerevisiae JEL1 harboring topoisomerase1 dele...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50261761(CHEMBL4096982)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of 3 nM recombinant human topoisomerase-2alpha catalytic activity expressed in Saccharomyces cerevisiae JEL1 harboring topoisomerase1 dele...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50261770(CHEMBL4069784)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-2alpha expressed in Saccharomyces cerevisiae JEL1 harboring topoisomerase1 deletion mutant assessed as ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50261770(CHEMBL4069784)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of ABCG2 in human H460/MX20 cells assessed as potentiation of mitoxantrone induced antiproliferative activity by measuring mitoxantrone IC...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50261769(CHEMBL4070811)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of 150 nM recombinant human topoisomerase-2alpha catalytic activity expressed in Saccharomyces cerevisiae JEL1 harboring topoisomerase1 de...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50261768(CHEMBL2436126)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of 3 nM recombinant human topoisomerase-2alpha catalytic activity expressed in Saccharomyces cerevisiae JEL1 harboring topoisomerase1 dele...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM79403(3-aminopropyl-[4-(3-aminopropylamino)butyl]amine;h...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of 3 nM recombinant human topoisomerase-2alpha catalytic activity expressed in Saccharomyces cerevisiae JEL1 harboring topoisomerase1 dele...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50009353(1,5,10-triazadecane | 4-azaoctamethylenediamine | ...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of 3 nM recombinant human topoisomerase-2alpha catalytic activity expressed in Saccharomyces cerevisiae JEL1 harboring topoisomerase1 dele...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed