Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50001975
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451411BDBM50451411(CHEMBL4205504)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451412BDBM50451412(CHEMBL4211801)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451414BDBM50451414(CHEMBL4208381)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451420BDBM50451420(CHEMBL4202984)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451407BDBM50451407(CHEMBL4211220)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451422BDBM50451422(CHEMBL4207174)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451409BDBM50451409(CHEMBL4204582)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451413BDBM50451413(CHEMBL4218068)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451408BDBM50451408(CHEMBL4204309)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451421BDBM50451421(CHEMBL4208775)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 114021BDBM114021(SMR000195898 | N-(3-carbazol-9-yl-2-hydroxypropyl)...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451406BDBM50451406(CHEMBL4206849)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451403BDBM50451403(CHEMBL4217236)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451417BDBM50451417(CHEMBL4202435)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451416BDBM50451416(CHEMBL4204042)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451401BDBM50451401(CHEMBL4206331)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451404BDBM50451404(CHEMBL4208507)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451405BDBM50451405(CHEMBL4218591)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451402BDBM50451402(CHEMBL4204985)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451400BDBM50451400(CHEMBL4212215)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451419BDBM50451419(CHEMBL4204085)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451410BDBM50451410(CHEMBL4218977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451418BDBM50451418(CHEMBL4215297)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451415BDBM50451415(CHEMBL4208920)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human BACE1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate measured after 60 mins by time-resolved fluorescence quenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed