Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50001400
TargetEpidermal growth factor receptor(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50278393(CHEMBL4176629)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human GST-tagged EGFR cytoplasmic domain (668 to 1210 residues) expressed in baculovirus virus expression system after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2020
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human His-tagged HER2 cytoplasmic domain (676 to 1255 residues) expressed in baculovirus virus expression system after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50278391(CHEMBL4166412)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human GST-tagged EGFR cytoplasmic domain (668 to 1210 residues) expressed in baculovirus virus expression system after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human GST-tagged EGFR cytoplasmic domain (668 to 1210 residues) expressed in baculovirus virus expression system after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50278392(CHEMBL4164936)
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant human GST-tagged EGFR cytoplasmic domain (668 to 1210 residues) expressed in baculovirus virus expression system after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2020
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50278393(CHEMBL4176629)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human His-tagged HER2 cytoplasmic domain (676 to 1255 residues) expressed in baculovirus virus expression system after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2020
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50278391(CHEMBL4166412)
Affinity DataIC50: 390nMAssay Description:Inhibition of recombinant human His-tagged HER2 cytoplasmic domain (676 to 1255 residues) expressed in baculovirus virus expression system after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2020
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50278392(CHEMBL4164936)
Affinity DataIC50: 760nMAssay Description:Inhibition of recombinant human His-tagged HER2 cytoplasmic domain (676 to 1255 residues) expressed in baculovirus virus expression system after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2020
Entry Details Article
PubMed