Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 50001435
LigandPNGBDBM50279327(CHEMBL4165288)
Affinity DataIC50: 100nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM8370(N-[6-(4-hydroxyphenyl)-1H-indazol-3-yl]cyclopropan...)
Affinity DataIC50: 100nMAssay Description:Inhibition of GSK3beta (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50279329(CHEMBL4161596)
Affinity DataIC50: 126nMAssay Description:Inhibition of PIM1 (unknown origin) using TAMRA-ERMRPRKRQGSVRRRV-NH2 as substrate pretreated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50279345(CHEMBL4172211)
Affinity DataIC50: 316nMAssay Description:Inhibition of PIM1 (unknown origin) using TAMRA-ERMRPRKRQGSVRRRV-NH2 as substrate pretreated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279329(CHEMBL4161596)
Affinity DataIC50: 501nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM8370(N-[6-(4-hydroxyphenyl)-1H-indazol-3-yl]cyclopropan...)
Affinity DataIC50: 501nMAssay Description:Inhibition of PIM1 (unknown origin) using TAMRA-ERMRPRKRQGSVRRRV-NH2 as substrate pretreated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50279345(CHEMBL4172211)
Affinity DataIC50: 631nMAssay Description:Inhibition of GSK3beta (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279347(CHEMBL4163479)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50279328(CHEMBL4176717)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of GSK3beta (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50279344(CHEMBL4174177)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of GSK3beta (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50279329(CHEMBL4161596)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of human GSK3beta using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279344(CHEMBL4174177)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50279344(CHEMBL4174177)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PIM1 (unknown origin) using TAMRA-ERMRPRKRQGSVRRRV-NH2 as substrate pretreated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50279327(CHEMBL4165288)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of PIM1 (unknown origin) using TAMRA-ERMRPRKRQGSVRRRV-NH2 as substrate pretreated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50279328(CHEMBL4176717)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of PIM1 (unknown origin) using TAMRA-ERMRPRKRQGSVRRRV-NH2 as substrate pretreated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50279327(CHEMBL4165288)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of GSK3beta (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279346(CHEMBL4175904)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279328(CHEMBL4176717)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279329(CHEMBL4161596)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279345(CHEMBL4172211)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279327(CHEMBL4165288)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279327(CHEMBL4165288)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50279347(CHEMBL4163479)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of GSK3beta (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279328(CHEMBL4176717)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279344(CHEMBL4174177)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279327(CHEMBL4165288)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279346(CHEMBL4175904)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50279326(CHEMBL4168859)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of PIM1 (unknown origin) using TAMRA-ERMRPRKRQGSVRRRV-NH2 as substrate pretreated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50279347(CHEMBL4163479)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of PIM1 (unknown origin) using TAMRA-ERMRPRKRQGSVRRRV-NH2 as substrate pretreated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279346(CHEMBL4175904)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50279327(CHEMBL4165288)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human GSK3beta using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279328(CHEMBL4176717)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279328(CHEMBL4176717)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279326(CHEMBL4168859)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM8370(N-[6-(4-hydroxyphenyl)-1H-indazol-3-yl]cyclopropan...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM8370(N-[6-(4-hydroxyphenyl)-1H-indazol-3-yl]cyclopropan...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279326(CHEMBL4168859)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279347(CHEMBL4163479)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279326(CHEMBL4168859)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279326(CHEMBL4168859)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279347(CHEMBL4163479)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM8370(N-[6-(4-hydroxyphenyl)-1H-indazol-3-yl]cyclopropan...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279329(CHEMBL4161596)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279329(CHEMBL4161596)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279345(CHEMBL4172211)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM8370(N-[6-(4-hydroxyphenyl)-1H-indazol-3-yl]cyclopropan...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279347(CHEMBL4163479)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279344(CHEMBL4174177)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279345(CHEMBL4172211)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50279345(CHEMBL4172211)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate pretreated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
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