Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with all data for entry = 50022563
TargetProtein arginine N-methyltransferase 5(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM178085(US9675614, 188 | US10307413, Compound 188 | US1039...)
Affinity DataIC50: 11nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of PRMT5/MEP50 complex from methylating histone 4 (H4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein arginine N-methyltransferase 5(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM178085(US9675614, 188 | US10307413, Compound 188 | US1039...)
Affinity DataEC50:  56nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of PRMT5/MEP50 complex from methylating SmD3More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)