Found 62 Enz. Inhib. hit(s) with all data for entry = 50001998 TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as reduction in 2-hydroxyglutarate production after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 5.60nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 7.5nMAssay Description:Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as reduction in 2-hydroxyglutarate production after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 7.5nMAssay Description:Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as reduction in 2-hydroxyglutarate productionMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as reduction in 2-hydroxyglutarate production after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as reduction in 2-hydroxyglutarate production after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as reduction in 2-hydroxyglutarate production after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as reduction in 2-hydroxyglutarate production after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as reduction in 2-hydroxyglutarate production after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as reduction in 2-hydroxyglutarate production after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as reduction in 2-hydroxyglutarate production after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin)More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as reduction in 2-hydroxyglutarate production after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as reduction in 2-hydroxyglutarate production after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as reduction in 2-hydroxyglutarate production after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as reduction in 2-hydroxyglutarate production after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as reduction in 2-hydroxyglutarate production after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as reduction in 2-hydroxyglutarate production after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as reduction in 2-hydroxyglutarate production after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 94nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 95nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: >100nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin) using alpha-ketoglutarate as substrate pretreated for 60 mins followed by substrate addition measure...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: >100nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin) using alpha-ketoglutarate as substrate pretreated for 60 mins followed by substrate addition measure...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 108nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 128nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 138nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 148nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 172nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 186nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 255nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 266nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe
Curated by ChEMBL
Shanghai Haihe
Curated by ChEMBL
Affinity DataIC50: 275nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
