Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50002005
TargetRap guanine nucleotide exchange factor 4(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452020BDBM50452020(CHEMBL4213611)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at recombinant full length EPAC2 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452008BDBM50452008(CHEMBL4214692)
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at recombinant full length EPAC2 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452021BDBM50452021(CHEMBL4210825)
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at recombinant full length EPAC2 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451963BDBM50451963(CHEMBL4216385)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at recombinant full length EPAC2 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452010BDBM50452010(CHEMBL4209582)
Affinity DataIC50: 3.40E+3nMAssay Description:Antagonist activity at recombinant full length EPAC2 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452020BDBM50452020(CHEMBL4213611)
Affinity DataIC50: 3.60E+3nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50280395BDBM50280395(CHEMBL4171480)
Affinity DataIC50: 4.20E+3nMAssay Description:Antagonist activity at recombinant human GST-fused EPAC1 (149 to 881 residues) expressed in Escherichia coli Rosetta (DE3) assessed as inhibition of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011360BDBM50011360(CHEMBL3260990)
Affinity DataIC50: 4.40E+3nMAssay Description:Antagonist activity at recombinant full length EPAC2 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451965BDBM50451965(CHEMBL4217436)
Affinity DataIC50: 5.40E+3nMAssay Description:Antagonist activity at recombinant full length EPAC2 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452021BDBM50452021(CHEMBL4210825)
Affinity DataIC50: 5.40E+3nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452009BDBM50452009(CHEMBL4205201)
Affinity DataIC50: 5.50E+3nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50280395BDBM50280395(CHEMBL4171480)
Affinity DataIC50: 5.50E+3nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451965BDBM50451965(CHEMBL4217436)
Affinity DataIC50: 5.60E+3nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451966BDBM50451966(CHEMBL4205731)
Affinity DataIC50: 6.10E+3nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452009BDBM50452009(CHEMBL4205201)
Affinity DataIC50: 6.30E+3nMAssay Description:Antagonist activity at recombinant full length EPAC2 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452010BDBM50452010(CHEMBL4209582)
Affinity DataIC50: 6.40E+3nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011360BDBM50011360(CHEMBL3260990)
Affinity DataIC50: 9.10E+3nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452008BDBM50452008(CHEMBL4214692)
Affinity DataIC50: 1.13E+4nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451964BDBM50451964(CHEMBL4214491)
Affinity DataIC50: 1.24E+4nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451966BDBM50451966(CHEMBL4205731)
Affinity DataIC50: 1.24E+4nMAssay Description:Antagonist activity at recombinant full length EPAC2 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452013BDBM50452013(CHEMBL4215769)
Affinity DataIC50: 1.33E+4nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451963BDBM50451963(CHEMBL4216385)
Affinity DataIC50: 1.39E+4nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452024BDBM50452024(CHEMBL4218696)
Affinity DataIC50: 1.46E+4nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451968BDBM50451968(CHEMBL4215455)
Affinity DataIC50: 1.58E+4nMAssay Description:Antagonist activity at recombinant full length EPAC2 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50280395BDBM50280395(CHEMBL4171480)
Affinity DataIC50: 1.70E+4nMAssay Description:Antagonist activity at recombinant full length EPAC2 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452014BDBM50452014(CHEMBL4217273)
Affinity DataIC50: 1.96E+4nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451968BDBM50451968(CHEMBL4215455)
Affinity DataIC50: 2.44E+4nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452013BDBM50452013(CHEMBL4215769)
Affinity DataIC50: 2.84E+4nMAssay Description:Antagonist activity at recombinant full length EPAC2 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451969BDBM50451969(CHEMBL4209871)
Affinity DataIC50: 2.93E+4nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452019BDBM50452019(CHEMBL4203532)
Affinity DataIC50: 3.24E+4nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452018BDBM50452018(CHEMBL4204114)
Affinity DataIC50: 3.94E+4nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452023BDBM50452023(CHEMBL4217870)
Affinity DataIC50: 4.09E+4nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452015BDBM50452015(CHEMBL4212609)
Affinity DataIC50: 5.08E+4nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452022BDBM50452022(CHEMBL4206634)
Affinity DataIC50: 3.00E+5nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451967BDBM50451967(CHEMBL4209371)
Affinity DataIC50: 3.00E+5nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452017BDBM50452017(CHEMBL4207208)
Affinity DataIC50: 3.00E+5nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452016BDBM50452016(CHEMBL4215366)
Affinity DataIC50: 3.00E+5nMAssay Description:Antagonist activity at recombinant full length EPAC1 (unknown origin) assessed as inhibition of cAMP-mediated Rap1b-BODIPY GDP nucleotide exchange ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed