Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50002889
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459778BDBM50459778(Ascofuranone | US11565996, Compound Ascochlorin)
Affinity DataKi:  0.130nMAssay Description:Inhibition of Trypanosoma brucei alternative oxidase expressed in Escherichia coli FN102 using ubiquinol-1 as substrate preincubated for 2 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50464455BDBM50464455(CHEMBL4294528 | US11565996, Compound Colletochlori...)
Affinity DataIC50: 3.98nMAssay Description:Inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 using 1-ubiquinol as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50464450BDBM50464450(CHEMBL4291644)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 using 1-ubiquinol as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50464455BDBM50464455(CHEMBL4294528 | US11565996, Compound Colletochlori...)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 using 1-ubiquinol as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50464443BDBM50464443(CHEMBL4292960)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 using 1-ubiquinol as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50464449BDBM50464449(CHEMBL4280758)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 using 1-ubiquinol as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50464456BDBM50464456(CHEMBL4282186)
Affinity DataIC50: 126nMAssay Description:Inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 using 1-ubiquinol as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50464446BDBM50464446(CHEMBL4292398)
Affinity DataIC50: 251nMAssay Description:Inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 using 1-ubiquinol as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50464454BDBM50464454(CHEMBL4283939)
Affinity DataIC50: 316nMAssay Description:Inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 using 1-ubiquinol as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50464453BDBM50464453(CHEMBL4282192)
Affinity DataIC50: 501nMAssay Description:Inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 using 1-ubiquinol as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50464444BDBM50464444(CHEMBL4277669)
Affinity DataIC50: 794nMAssay Description:Inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 using 1-ubiquinol as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50464447BDBM50464447(CHEMBL4292788)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 using 1-ubiquinol as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50464457BDBM50464457(CHEMBL4283459)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 using 1-ubiquinol as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50464459BDBM50464459(CHEMBL4278723)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 using 1-ubiquinol as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50464445BDBM50464445(CHEMBL4277675)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 using 1-ubiquinol as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50464452BDBM50464452(CHEMBL4293869)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 using 1-ubiquinol as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50464448BDBM50464448(CHEMBL4285614)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 using 1-ubiquinol as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50464458BDBM50464458(CHEMBL4285973)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 using 1-ubiquinol as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University of Sussex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50464451BDBM50464451(CHEMBL4289387)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 using 1-ubiquinol as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed