Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50022649
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 0.430nMAssay Description:Inhibition of human CDK6/cyclin D1 preincubated with compound for 20 mins followed by [33P]ATP addition and measured after 2 hrs by filter binding me...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 0.430nMAssay Description:Inhibition of human CDK6/cyclin D1 preincubated with compound for 20 mins followed by [33P]ATP addition and measured after 2 hrs by filter binding me...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human CDK4/cyclin D1 preincubated with compound for 20 mins followed by [33P]ATP addition and measured after 2 hrs by filter binding me...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of CDK4/cyclin D1 (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human CDK4/cyclin D1 preincubated with compound for 20 mins followed by [33P]ATP addition and measured after 2 hrs by filter binding me...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of CDK6/cyclin D1 (unknown origin)More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human CAMK2delta preincubated with compound for 20 mins followed by [33P]ATP addition and measured after 2 hrs by filter binding methodMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human CAMK2beta preincubated with compound for 20 mins followed by [33P]ATP addition and measured after 2 hrs by filter binding methodMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human CDK6/cyclin D3 preincubated with compound for 20 mins followed by [33P]ATP addition and measured after 2 hrs by filter binding me...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human CDK4/cyclin D3 preincubated with compound for 20 mins followed by [33P]ATP addition and measured after 2 hrs by filter binding me...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human CDK4/cyclin D3 preincubated with compound for 20 mins followed by [33P]ATP addition and measured after 2 hrs by filter binding me...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human GSK3beta preincubated with compound for 20 mins followed by [33P]ATP addition and measured after 2 hrs by filter binding methodMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:Inhibition of human CDK6/cyclin D3 preincubated with compound for 20 mins followed by [33P]ATP addition and measured after 2 hrs by filter binding me...More data for this Ligand-Target Pair
TargetHomeodomain-interacting protein kinase 2(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of HIPK2 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit gamma(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of human CAMK2gamma preincubated with compound for 20 mins followed by [33P]ATP addition and measured after 2 hrs by filter binding methodMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 61nMAssay Description:Inhibition of DYRK2 (unknown origin)More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 117nMAssay Description:Inhibition of CSNK2A1 (unknown origin)More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 192nMAssay Description:Inhibition of GSK3B (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 287nMAssay Description:Inhibition of CDK5/p35 (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 355nMAssay Description:Inhibition of CDK5/p25 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 389nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 403nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 504nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin)More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 610nMAssay Description:Inhibition of human CAMK2delta preincubated with compound for 20 mins followed by [33P]ATP addition and measured after 2 hrs by filter binding methodMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 17A(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 659nMAssay Description:Inhibition of DRAK1 (unknown origin)More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human CAMK2beta preincubated with compound for 20 mins followed by [33P]ATP addition and measured after 2 hrs by filter binding methodMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of CDK1/cyclin B1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-2(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of PIM2 (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 3.91E+3nMAssay Description:Inhibition of CDK7/CycH/MAT1 (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 3.96E+3nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 6.33E+3nMAssay Description:Inhibition of BRAF (unknown origin)More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit gamma(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human CAMK2gamma preincubated with compound for 20 mins followed by [33P]ATP addition and measured after 2 hrs by filter binding methodMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of human GSK3beta preincubated with compound for 20 mins followed by [33P]ATP addition and measured after 2 hrs by filter binding methodMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK3(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PLK3 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CRAF (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of AURKB (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of AURKA (unknown origin)More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 3(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
