Compile Data Set for Download or QSAR
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Found 7 Enz. Inhib. hit(s) with all data for entry = 50000473
TargetCytochrome P450 2C8(Homo sapiens (Human))
Medifron Dbt

Curated by ChEMBL
LigandPNGBDBM50250939(CHEMBL4066961)
Affinity DataIC50:  3.14E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes preincubated for 5 mins followed by addition of NADPH generating system measured after 20 mins by LC-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Medifron Dbt

Curated by ChEMBL
LigandPNGBDBM50250939(CHEMBL4066961)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes preincubated for 5 mins followed by addition of NADPH generating system measured after 20 mins by LC-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Medifron Dbt

Curated by ChEMBL
LigandPNGBDBM50250939(CHEMBL4066961)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of JAK1 in IL6-stimulated human ME180 cells expressing stably integrated beta-lactamase reporter gene under control of sis-inducible eleme...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Medifron Dbt

Curated by ChEMBL
LigandPNGBDBM50250939(CHEMBL4066961)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes preincubated for 5 mins followed by addition of NADPH generating system measured after 20 mins by LC-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Medifron Dbt

Curated by ChEMBL
LigandPNGBDBM50250939(CHEMBL4066961)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes preincubated for 5 mins followed by addition of NADPH generating system measured after 20 mins by LC-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Medifron Dbt

Curated by ChEMBL
LigandPNGBDBM50250939(CHEMBL4066961)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes preincubated for 5 mins followed by addition of NADPH generating system measured after 20 mins by LC-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Medifron Dbt

Curated by ChEMBL
LigandPNGBDBM50250939(CHEMBL4066961)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes preincubated for 5 mins followed by addition of NADPH generating system measured after 20 mins by LC-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed