Compile Data Set for Download or QSAR
maximum 50k data
Found 45 Enz. Inhib. hit(s) with all data for entry = 50002138
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  200nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human MNC suspension after 20 hrs by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454030(CHEMBL4214663)
Affinity DataIC50:  300nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453983(CHEMBL4215614)
Affinity DataIC50:  500nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  500nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454032(CHEMBL4209925)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454026(CHEMBL4216705)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453998(CHEMBL4206211)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453997(CHEMBL4204861)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453995(CHEMBL4212779)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454033(CHEMBL4211218)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453993(CHEMBL4206607)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453988(CHEMBL4202770)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454006(CHEMBL4213788)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453991(CHEMBL4211883)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453990(CHEMBL4209097)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454000(CHEMBL4204753)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453992(CHEMBL4216524)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454028(CHEMBL4216431)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454008(CHEMBL4217242)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454004(CHEMBL4213498)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Mus musculus)
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454023(CHEMBL4215786)
Affinity DataIC50:  1.65E+4nMAssay Description:Inhibition of mouse recombinant TNF-alpha binding to antibody preincubated for 30 mins followed by antibody addition measured after 2 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453986(CHEMBL4212953)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454025(CHEMBL4208862)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453994(CHEMBL4211594)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454005(CHEMBL4208563)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50373071(CHEMBL255489)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of TNF-alpha (unknown origin) binding to TNFR1 by ELISAMore data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453987(CHEMBL4203548)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454022(CHEMBL4206575)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453985(CHEMBL4208400)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453989(CHEMBL4204234)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454021(CHEMBL4217876)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454002(CHEMBL4204718)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454001(CHEMBL4205907)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454024(CHEMBL4217894)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453999(CHEMBL4204426)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454027(CHEMBL4212813)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453984(CHEMBL4212933)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454031(CHEMBL4215621)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454029(CHEMBL4214427)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453982(CHEMBL4207994)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50453996(CHEMBL4204585)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454020(CHEMBL4207908)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454007(CHEMBL4212270)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454003(CHEMBL4204400)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Padmashri Vikhe Patil College Of Arts

Curated by ChEMBL
LigandPNGBDBM50454009(CHEMBL4218009)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed