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Found 14 Enz. Inhib. hit(s) with all data for entry = 50002039
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Poznan University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha level using arachidonic acid as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Poznan University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50452602(CHEMBL4213360)
Affinity DataIC50:  279nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha level using arachidonic acid as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Poznan University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50452601(CHEMBL4206988)
Affinity DataIC50:  659nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGF2alpha level using arachidonic acid as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Poznan University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50452599(CHEMBL314774)
Affinity DataIC50:  2.17E+3nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha level using arachidonic acid as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Poznan University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50452599(CHEMBL314774)
Affinity DataIC50:  2.67E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGF2alpha level using arachidonic acid as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Poznan University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50452600(CHEMBL4206085)
Affinity DataIC50:  4.02E+3nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha level using arachidonic acid as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Poznan University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50452601(CHEMBL4206988)
Affinity DataIC50:  4.69E+3nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha level using arachidonic acid as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Poznan University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50452598(CHEMBL4218075)
Affinity DataIC50:  7.46E+3nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha level using arachidonic acid as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Poznan University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50452604(CHEMBL4216426)
Affinity DataIC50:  7.52E+3nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha level using arachidonic acid as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Poznan University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  8.22E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGF2alpha level using arachidonic acid as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Poznan University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50452602(CHEMBL4213360)
Affinity DataIC50:  1.75E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGF2alpha level using arachidonic acid as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Poznan University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50452598(CHEMBL4218075)
Affinity DataIC50:  4.08E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGF2alpha level using arachidonic acid as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Poznan University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50452604(CHEMBL4216426)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGF2alpha level using arachidonic acid as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Poznan University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50452600(CHEMBL4206085)
Affinity DataIC50:  8.50E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGF2alpha level using arachidonic acid as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed