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Found 16 Enz. Inhib. hit(s) with all data for entry = 50001480
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Pretoria

Curated by ChEMBL
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  1.00E+4nMAssay Description:Antibacterial activity against D-alanyl-D-alanine ligase from Streptococcus faecalis (ATCC 8043)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Pretoria

Curated by ChEMBL
LigandPNGBDBM50217942(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chr...)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate measured at 1 min interval by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Pretoria

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Pretoria

Curated by ChEMBL
LigandPNGBDBM153266(5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy...)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate pretreated for 5 mins followed by substrate addition measured over 30 mins by spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Pretoria

Curated by ChEMBL
LigandPNGBDBM50217942(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chr...)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate pretreated for 5 mins followed by substrate addition measured over 30 mins by spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Pretoria

Curated by ChEMBL
LigandPNGBDBM50351096(ASCORBIC ACID)
Affinity DataIC50:  1.44E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate pretreated for 5 mins followed by substrate addition measured over 30 mins by spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Pretoria

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate pretreated for 5 mins followed by substrate addition measured over 30 mins by spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Pretoria

Curated by ChEMBL
LigandPNGBDBM50280377(CHEMBL4172192)
Affinity DataIC50:  1.80E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate pretreated for 5 mins followed by substrate addition measured over 30 mins by spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Pretoria

Curated by ChEMBL
LigandPNGBDBM50280375(CHEMBL4176025)
Affinity DataIC50:  1.90E+5nMAssay Description:Inhibitory activity against Herpes simplex virus type-I specific thymidine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Pretoria

Curated by ChEMBL
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)
Affinity DataIC50:  2.10E+5nMAssay Description:Binding affinity of compound against Phencyclidine receptor by displacement of [3H]TCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Pretoria

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  2.40E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate pretreated for 5 mins followed by substrate addition measured over 30 mins by spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Pretoria

Curated by ChEMBL
LigandPNGBDBM50280376(CHEMBL4167746)
Affinity DataIC50:  2.80E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate pretreated for 5 mins followed by substrate addition measured over 30 mins by spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Pretoria

Curated by ChEMBL
LigandPNGBDBM50446574(CHEMBL3109438)
Affinity DataIC50:  3.10E+5nMAssay Description:Binding affinity of compound against Phencyclidine receptor by displacement of [3H]TCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Pretoria

Curated by ChEMBL
LigandPNGBDBM153266(5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy...)
Affinity DataIC50:  3.20E+5nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Pretoria

Curated by ChEMBL
LigandPNGBDBM50280378(CHEMBL4168843)
Affinity DataIC50:  4.10E+5nMAssay Description:Inhibition of compound against spermidine synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Pretoria

Curated by ChEMBL
LigandPNGBDBM50280379(CHEMBL4164304)
Affinity DataIC50:  5.20E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate pretreated for 5 mins followed by substrate addition measured over 30 mins by spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed