Found 38 Enz. Inhib. hit(s) with all data for entry = 50011517 
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of recombinant CYP2C8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using testosterone as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Agonist activity at rat GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye based ...More data for this Ligand-Target Pair
Affinity DataEC50: 24nMAssay Description:Agonist activity at rat GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye based ...More data for this Ligand-Target Pair
Affinity DataEC50: 32nMAssay Description:Agonist activity at rat GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye based ...More data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Agonist activity at rat GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye based ...More data for this Ligand-Target Pair
Affinity DataEC50: 49nMAssay Description:Agonist activity at rat GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye based ...More data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Agonist activity at rat GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye based ...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Research & Developmen
Curated by ChEMBL
Janssen Research & Developmen
Curated by ChEMBL
Affinity DataEC50: 11nMAssay Description:Agonist activity at human GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye base...More data for this Ligand-Target Pair
Affinity DataEC50: 70nMAssay Description:Agonist activity at rat GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye based ...More data for this Ligand-Target Pair
Affinity DataEC50: 64nMAssay Description:Agonist activity at rat GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye based ...More data for this Ligand-Target Pair
Affinity DataEC50: 45nMAssay Description:Agonist activity at rat GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye based ...More data for this Ligand-Target Pair
Affinity DataEC50: 46nMAssay Description:Agonist activity at rat GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye based ...More data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Agonist activity at rat GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye based ...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Research & Developmen
Curated by ChEMBL
Janssen Research & Developmen
Curated by ChEMBL
Affinity DataEC50: 2.5nMAssay Description:Agonist activity at human GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye base...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Research & Developmen
Curated by ChEMBL
Janssen Research & Developmen
Curated by ChEMBL
Affinity DataEC50: 7.5nMAssay Description:Agonist activity at human GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye base...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Research & Developmen
Curated by ChEMBL
Janssen Research & Developmen
Curated by ChEMBL
Affinity DataEC50: 4.5nMAssay Description:Agonist activity at human GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye base...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Research & Developmen
Curated by ChEMBL
Janssen Research & Developmen
Curated by ChEMBL
Affinity DataEC50: 9.60nMAssay Description:Agonist activity at human GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye base...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Research & Developmen
Curated by ChEMBL
Janssen Research & Developmen
Curated by ChEMBL
Affinity DataEC50: 2nMAssay Description:Agonist activity at human GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye base...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Research & Developmen
Curated by ChEMBL
Janssen Research & Developmen
Curated by ChEMBL
Affinity DataEC50: 2nMAssay Description:Agonist activity at human GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye base...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Research & Developmen
Curated by ChEMBL
Janssen Research & Developmen
Curated by ChEMBL
Affinity DataEC50: 9.40nMAssay Description:Agonist activity at human GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye base...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Research & Developmen
Curated by ChEMBL
Janssen Research & Developmen
Curated by ChEMBL
Affinity DataEC50: 11nMAssay Description:Agonist activity at human GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye base...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Research & Developmen
Curated by ChEMBL
Janssen Research & Developmen
Curated by ChEMBL
Affinity DataEC50: 37nMAssay Description:Agonist activity at human GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye base...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Research & Developmen
Curated by ChEMBL
Janssen Research & Developmen
Curated by ChEMBL
Affinity DataEC50: 12nMAssay Description:Agonist activity at human GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye base...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Research & Developmen
Curated by ChEMBL
Janssen Research & Developmen
Curated by ChEMBL
Affinity DataEC50: 21nMAssay Description:Agonist activity at human GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye base...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Research & Developmen
Curated by ChEMBL
Janssen Research & Developmen
Curated by ChEMBL
Affinity DataEC50: 9.40nMAssay Description:Agonist activity at human GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye base...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Research & Developmen
Curated by ChEMBL
Janssen Research & Developmen
Curated by ChEMBL
Affinity DataEC50: 3.5nMAssay Description:Agonist activity at human GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye base...More data for this Ligand-Target Pair
Affinity DataEC50: 31nMAssay Description:Agonist activity at rat GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye based ...More data for this Ligand-Target Pair
Affinity DataEC50: 28nMAssay Description:Agonist activity at rat GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye based ...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Research & Developmen
Curated by ChEMBL
Janssen Research & Developmen
Curated by ChEMBL
Affinity DataEC50: 894nMAssay Description:Agonist activity at human GPR40 receptor expressed in CHOK1 cells assessed as induction of IP1 accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 547nMAssay Description:Agonist activity at rat GPR40 receptor expressed in CHOK1 cells assessed as induction of IP1 accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 8.62E+5nMAssay Description:Agonist activity at GPR40 receptor in rat INS1(832/13) cells assessed as induction of IP1 accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 38nMAssay Description:Agonist activity at mouse GPR40 assessed as increase in intracellular calcium levelMore data for this Ligand-Target Pair
Affinity DataEC50: 201nMAssay Description:Agonist activity at rat GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye based ...More data for this Ligand-Target Pair
