Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50002191
TargetOxysterols receptor LXR-alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19993BDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human LXRalpha expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19993BDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454837BDBM50454837(CHEMBL4217784)
Affinity DataEC50:  40nMAssay Description:Agonist activity at LXRbeta ligand-binding domain (unknown origin) incubated for 1.5 hrs using fluorescein-labeled coactivator peptide by TR-FRET com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454838BDBM50454838(CHEMBL4215604)
Affinity DataEC50:  270nMAssay Description:Agonist activity at human LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Mouse)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454838BDBM50454838(CHEMBL4215604)
Affinity DataEC50:  300nMAssay Description:Agonist activity at mouse LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454837BDBM50454837(CHEMBL4217784)
Affinity DataEC50:  559nMAssay Description:Agonist activity at human LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Mouse)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454837BDBM50454837(CHEMBL4217784)
Affinity DataEC50:  790nMAssay Description:Agonist activity at mouse LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Mouse)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454839BDBM50454839(CHEMBL4217636)
Affinity DataEC50:  820nMAssay Description:Agonist activity at mouse LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454839BDBM50454839(CHEMBL4217636)
Affinity DataEC50:  915nMAssay Description:Agonist activity at human LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454833BDBM50454833(CHEMBL4207540)
Affinity DataEC50:  1.73E+3nMAssay Description:Agonist activity at human LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Mouse)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454841BDBM50454841(CHEMBL4204457)
Affinity DataEC50:  2.93E+3nMAssay Description:Agonist activity at mouse LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454841BDBM50454841(CHEMBL4204457)
Affinity DataEC50:  3.61E+3nMAssay Description:Agonist activity at human LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454843BDBM50454843(CHEMBL4215212)
Affinity DataEC50:  4.67E+3nMAssay Description:Agonist activity at human LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454842BDBM50454842(CHEMBL4215929)
Affinity DataEC50:  4.77E+3nMAssay Description:Agonist activity at human LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454835BDBM50454835(CHEMBL4214029)
Affinity DataEC50:  4.96E+3nMAssay Description:Agonist activity at human LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298686BDBM50298686(4,5,6,7-Tetrachloro-N-[2-(2-phenylethyl)phenyl]pht...)
Affinity DataEC50:  4.98E+3nMAssay Description:Agonist activity at human LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454834BDBM50454834(CHEMBL4213362)
Affinity DataEC50:  8.00E+3nMAssay Description:Agonist activity at human LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454832BDBM50454832(CHEMBL4212022)
Affinity DataEC50:  8.98E+3nMAssay Description:Agonist activity at human LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454840BDBM50454840(CHEMBL4208321)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454836BDBM50454836(CHEMBL4218494)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed