Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 50002726
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462183(CHEMBL3736320)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of ABL (unknown origin) by phosphocellulose paper disk assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462183(CHEMBL3736320)
Affinity DataIC50:  2nMAssay Description:Inhibition of full length FLAG-tagged BRAF V600E mutant (unknown origin) expressed in HEK293 cells assessed as decrease in MEK phosphorylation by imm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462182(CHEMBL4247506)
Affinity DataIC50:  3nMAssay Description:Inhibition of ABL (unknown origin) by phosphocellulose paper disk assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462188(CHEMBL4248365)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of ABL (unknown origin) by phosphocellulose paper disk assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462183(CHEMBL3736320)
Affinity DataIC50:  4nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) after 20 mins by immunoblotting assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462185(CHEMBL4237900)
Affinity DataIC50:  7nMAssay Description:Inhibition of ABL (unknown origin) by phosphocellulose paper disk assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462183(CHEMBL3736320)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of BCR-ABL (unknown origin) expressed in mouse BA/F3 cells assessed as reduction in ABL phosphorylation at Y412 residue incubated for 3 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462183(CHEMBL3736320)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of BCR-ABL (unknown origin) expressed in mouse BA/F3 cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462187(CHEMBL4242050)
Affinity DataIC50:  10nMAssay Description:Inhibition of ABL (unknown origin) by phosphocellulose paper disk assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462188(CHEMBL4248365)
Affinity DataIC50:  13nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) after 20 mins by immunoblotting assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462182(CHEMBL4247506)
Affinity DataIC50:  14nMAssay Description:Inhibition of full length FLAG-tagged BRAF V600E mutant (unknown origin) expressed in HEK293 cells assessed as decrease in MEK phosphorylation by imm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | US10570155, Vemu...)
Affinity DataIC50:  21nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) after 20 mins by immunoblotting assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462184(CHEMBL4250674)
Affinity DataIC50:  22nMAssay Description:Inhibition of ABL (unknown origin) by phosphocellulose paper disk assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462189(CHEMBL4249028)
Affinity DataIC50:  24nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) after 20 mins by immunoblotting assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462187(CHEMBL4242050)
Affinity DataIC50:  44nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) after 20 mins by immunoblotting assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462186(CHEMBL4243230)
Affinity DataIC50:  46nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) after 20 mins by immunoblotting assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462185(CHEMBL4237900)
Affinity DataIC50:  51nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) after 20 mins by immunoblotting assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462182(CHEMBL4247506)
Affinity DataIC50:  65nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) after 20 mins by immunoblotting assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462184(CHEMBL4250674)
Affinity DataIC50:  87nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) after 20 mins by immunoblotting assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462183(CHEMBL3736320)
Affinity DataIC50:  97nMAssay Description:Inhibition of BRAF V600E mutant in human A375 cells assessed as reduction in cell proliferation incubated for 96 hrs by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | US10570155, Vemu...)
Affinity DataIC50:  127nMAssay Description:Inhibition of BRAF V600E mutant in human A375 cells assessed as reduction in cell proliferation incubated for 96 hrs by MTT assayMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462185(CHEMBL4237900)
Affinity DataIC50:  211nMAssay Description:Inhibition of BCR-ABL (unknown origin) expressed in mouse BA/F3 cells assessed as reduction in ABL phosphorylation at Y412 residue incubated for 3 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462185(CHEMBL4237900)
Affinity DataIC50:  354nMAssay Description:Inhibition of BCR-ABL (unknown origin) expressed in mouse BA/F3 cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462187(CHEMBL4242050)
Affinity DataIC50:  435nMAssay Description:Inhibition of BCR-ABL (unknown origin) expressed in mouse BA/F3 cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462182(CHEMBL4247506)
Affinity DataIC50:  942nMAssay Description:Inhibition of BCR-ABL (unknown origin) expressed in mouse BA/F3 cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462188(CHEMBL4248365)
Affinity DataIC50:  1.11E+3nMAssay Description:Inhibition of BCR-ABL (unknown origin) expressed in mouse BA/F3 cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462187(CHEMBL4242050)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of BRAF V600E mutant in human A375 cells assessed as reduction in cell proliferation incubated for 96 hrs by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462185(CHEMBL4237900)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BRAF V600E mutant in human A375 cells assessed as reduction in cell proliferation incubated for 96 hrs by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462188(CHEMBL4248365)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BRAF V600E mutant in human A375 cells assessed as reduction in cell proliferation incubated for 96 hrs by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50462182(CHEMBL4247506)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BRAF V600E mutant in human A375 cells assessed as reduction in cell proliferation incubated for 96 hrs by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB