Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50002408
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458238(CHEMBL4203703)
Affinity DataIC50: 0.730nMAssay Description:Antagonist activity at CXCR4 in human CD4+ T cells assessed as inhibition of CXCL12-mediated cytosolic calcium level preincubated with compounds foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458252(CHEMBL4214960)
Affinity DataIC50: 2.30nMAssay Description:Antagonist activity at CXCR4 in human CD4+ T cells assessed as inhibition of CXCL12-mediated cytosolic calcium level preincubated with compounds foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458240(CHEMBL4214538)
Affinity DataIC50: 18nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50035696(AMD-3100 | CHEMBL18442 | 11-{4-[4,8, 11-1,4,8,11te...)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at CXCR4 in human CD4+ T cells assessed as inhibition of CXCL12-mediated cytosolic calcium level preincubated with compounds foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458241(CHEMBL4203303)
Affinity DataIC50: 18nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458252(CHEMBL4214960)
Affinity DataIC50: 54nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458251(CHEMBL4215380)
Affinity DataIC50: 68nMAssay Description:Antagonist activity at CXCR4 in human CD4+ T cells assessed as inhibition of CXCL12-mediated cytosolic calcium level preincubated with compounds foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458238(CHEMBL4203703)
Affinity DataIC50: 88nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458236(CHEMBL4207399)
Affinity DataIC50: 150nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458249(CHEMBL4211758)
Affinity DataIC50: 170nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458237(CHEMBL4207126)
Affinity DataIC50: 180nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458235(CHEMBL4207646)
Affinity DataIC50: 200nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458256(CHEMBL4216789)
Affinity DataIC50: 210nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458248(CHEMBL4206872)
Affinity DataIC50: 290nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50035696(AMD-3100 | CHEMBL18442 | 11-{4-[4,8, 11-1,4,8,11te...)
Affinity DataIC50: 290nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458247(CHEMBL4203042)
Affinity DataIC50: 320nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458239(CHEMBL4202510)
Affinity DataIC50: 630nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458250(CHEMBL4218715)
Affinity DataIC50: 640nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458255(CHEMBL4213783)
Affinity DataIC50: 1.02E+3nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458254(CHEMBL4215245)
Affinity DataIC50: 1.05E+3nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458251(CHEMBL4215380)
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458246(CHEMBL4209872)
Affinity DataIC50: 2.60E+3nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458244(CHEMBL4211489)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458243(CHEMBL4210451)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458257(CHEMBL4203626)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458245(CHEMBL4214030)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458242(CHEMBL4202776)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458253(CHEMBL4218952)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of 12G5-CXCL12 from CXCR4 in human HPBALL cells after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50458238(CHEMBL4203703)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells after 4 mins at -80 mV holding potential by Qpatch assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed