Compile Data Set for Download or QSAR
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Found 36 Enz. Inhib. hit(s) with all data for entry = 50000631
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of fluormone VDR red from human full length VDR after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256338(CHEMBL4103687)
Affinity DataIC50:  228nMAssay Description:Displacement of fluormone VDR red from human full length VDR after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256336(CHEMBL4102275)
Affinity DataIC50:  271nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256334(CHEMBL4075907)
Affinity DataIC50:  296nMAssay Description:Displacement of fluormone VDR red from human full length VDR after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256340(CHEMBL4101362)
Affinity DataIC50:  406nMAssay Description:Inhibition of plasma kallikrein in human plasma using HMWK as substrate assessed as suppression of kaolin-activated protein induced bradykinin releas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256337(CHEMBL4078012)
Affinity DataIC50:  825nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256307(CHEMBL4097419)
Affinity DataIC50:  873nMAssay Description:Displacement of fluormone VDR red from human full length VDR after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256294(CHEMBL4073404)
Affinity DataIC50:  4.54E+3nMAssay Description:Displacement of fluormone VDR red from human full length VDR after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256308(CHEMBL4101251)
Affinity DataEC50:  66nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256309(CHEMBL4074522)
Affinity DataEC50:  450nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256310(CHEMBL4063153)
Affinity DataEC50:  53nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256333(CHEMBL4085761)
Affinity DataEC50:  96nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataEC50:  9nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256339(CHEMBL4074357)
Affinity DataEC50:  5nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256336(CHEMBL4102275)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256337(CHEMBL4078012)
Affinity DataEC50:  1.08E+3nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256340(CHEMBL4101362)
Affinity DataEC50:  238nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256341(CHEMBL4085890)
Affinity DataEC50:  82nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256342(CHEMBL4083376)
Affinity DataEC50:  156nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256343(CHEMBL4078953)
Affinity DataEC50:  2.65E+3nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256344(CHEMBL4094053)
Affinity DataEC50:  5.90E+3nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256345(CHEMBL4083785)
Affinity DataEC50:  520nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256346(CHEMBL4079382)
Affinity DataEC50:  26nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256347(CHEMBL4084799)
Affinity DataEC50:  2.49E+3nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256338(CHEMBL4103687)
Affinity DataEC50:  8.5nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256307(CHEMBL4097419)
Affinity DataEC50:  89nMAssay Description:Displacement of fluormone VDR red from human full length VDR after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256334(CHEMBL4075907)
Affinity DataEC50:  11nMAssay Description:Displacement of fluormone VDR red from human full length VDR after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256297(CHEMBL4091572)
Affinity DataEC50:  860nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256296(CHEMBL4063772)
Affinity DataEC50:  21nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256295(CHEMBL4101788)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256294(CHEMBL4073404)
Affinity DataEC50:  1.63E+3nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256293(CHEMBL4075991)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256292(CHEMBL4086285)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256291(CHEMBL4096970)
Affinity DataEC50:  6.03E+3nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256289(CHEMBL4072930)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50256290(CHEMBL4093629)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed