Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50002953
TargetHistone deacetylase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of HDAC in human K562 cells using Boc-K(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50300028(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
Affinity DataIC50: 4.56E+3nMAssay Description:Inhibition of G9a in human MDA-MB-231 cells assessed as reduction in H3K9me2 level after 2 days by immunofluorescence in-cell western analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 5.04E+3nMAssay Description:Inhibition of HDAC in human HeLa cells using Boc-K(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465081(CHEMBL4294122)
Affinity DataIC50: 5.74E+3nMAssay Description:Inhibition of HDAC in human K562 cells using Boc-K(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465081(CHEMBL4294122)
Affinity DataIC50: 7.14E+3nMAssay Description:Inhibition of G9a in human MDA-MB-231 cells assessed as reduction in H3K9me2 level after 2 days by immunofluorescence in-cell western analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465081(CHEMBL4294122)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of HDAC in human HeLa cells using Boc-K(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465086(CHEMBL4286227)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of HDAC in human HeLa cells using Boc-K(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465082(CHEMBL4292218)
Affinity DataIC50: 2.74E+4nMAssay Description:Inhibition of G9a in human MDA-MB-231 cells assessed as reduction in H3K9me2 level after 2 days by immunofluorescence in-cell western analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465086(CHEMBL4286227)
Affinity DataIC50: 2.78E+4nMAssay Description:Inhibition of HDAC in human K562 cells using Boc-K(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465086(CHEMBL4286227)
Affinity DataIC50: 3.78E+4nMAssay Description:Inhibition of G9a in human MDA-MB-231 cells assessed as reduction in H3K9me2 level after 2 days by immunofluorescence in-cell western analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465085(CHEMBL4282835)
Affinity DataIC50: 4.68E+4nMAssay Description:Inhibition of G9a in human MDA-MB-231 cells assessed as reduction in H3K9me2 level after 2 days by immunofluorescence in-cell western analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465083(CHEMBL4290721)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of G9a in human MDA-MB-231 cells assessed as reduction in H3K9me2 level after 2 days by immunofluorescence in-cell western analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465084(CHEMBL4284312)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC in human A549 cells using Boc-K(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC in human A549 cells using Boc-K(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465086(CHEMBL4286227)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC in human A549 cells using Boc-K(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465081(CHEMBL4294122)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC in human A549 cells using Boc-K(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465084(CHEMBL4284312)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC in human HeLa cells using Boc-K(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465084(CHEMBL4284312)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC in human K562 cells using Boc-K(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed