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Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 50002228
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM14774(3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl...)
Affinity DataIC50:  0.890nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM14774(3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455383(CHEMBL4215772)
Affinity DataIC50:  880nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455384(CHEMBL4206423)
Affinity DataIC50:  950nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455386(CHEMBL4213076)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  1.22E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  1.43E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455391(CHEMBL4215240)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455394(CHEMBL4208161)
Affinity DataIC50:  2.38E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455396(CHEMBL4211564)
Affinity DataIC50:  2.85E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455389(CHEMBL4216542)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455397(CHEMBL4217492)
Affinity DataIC50:  3.25E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455388(CHEMBL4205250)
Affinity DataIC50:  3.42E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455386(CHEMBL4213076)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455382(CHEMBL4210402)
Affinity DataIC50:  8.05E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455401(CHEMBL4210828)
Affinity DataIC50:  8.35E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455390(CHEMBL4206447)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455384(CHEMBL4206423)
Affinity DataIC50:  1.17E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455400(CHEMBL4212232)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455394(CHEMBL4208161)
Affinity DataIC50:  1.33E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455397(CHEMBL4217492)
Affinity DataIC50:  1.63E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455399(CHEMBL4205521)
Affinity DataIC50:  1.64E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455396(CHEMBL4211564)
Affinity DataIC50:  1.83E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455395(CHEMBL4204765)
Affinity DataIC50:  1.84E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455383(CHEMBL4215772)
Affinity DataIC50:  1.84E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455388(CHEMBL4205250)
Affinity DataIC50:  1.86E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455387(CHEMBL4209631)
Affinity DataIC50:  1.97E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455385(CHEMBL4216965)
Affinity DataIC50:  2.05E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455391(CHEMBL4215240)
Affinity DataIC50:  3.27E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455389(CHEMBL4216542)
Affinity DataIC50:  4.36E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455392(CHEMBL4203037)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455393(CHEMBL4207920)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455398(CHEMBL4203562)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455395(CHEMBL4204765)
Affinity DataIC50:  9.26E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455384(CHEMBL4206423)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE11AMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455384(CHEMBL4206423)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE9A2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455384(CHEMBL4206423)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE6CMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455383(CHEMBL4215772)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE2AMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455383(CHEMBL4215772)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE10A2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455383(CHEMBL4215772)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE9A2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455383(CHEMBL4215772)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE7AMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455384(CHEMBL4206423)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE7AMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455383(CHEMBL4215772)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE6CMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455383(CHEMBL4215772)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE5AMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455383(CHEMBL4215772)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE3BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455384(CHEMBL4206423)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE2AMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

LigandPNGBDBM50455384(CHEMBL4206423)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE1AMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455383(CHEMBL4215772)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE11AMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455384(CHEMBL4206423)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE8A1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455384(CHEMBL4206423)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE3BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

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