BindingDB PrimarySearch_ki

Found 55 Enz. Inhib. hit(s) with all data for entry = 50002228

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM14774(3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl...)

IC50: 0.890nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Purchase ChEBI
CHEMBL DrugBank MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM14774(3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl...)

IC50: 1.10nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase ChEBI
CHEMBL DrugBank MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed DrugBank
PDB

3D Structure (crystal)

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455383(CHEMBL4215772)

IC50: 880nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455384(CHEMBL4206423)

IC50: 950nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455386(CHEMBL4213076)

IC50: 1.05E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)

IC50: 1.22E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Purchase ChEBI
CHEMBL MCE
PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)

IC50: 1.43E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase ChEBI
CHEMBL MCE
PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455391(CHEMBL4215240)

IC50: 1.62E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455394(CHEMBL4208161)

IC50: 2.38E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455396(CHEMBL4211564)

IC50: 2.85E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455389(CHEMBL4216542)

IC50: 3.10E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455397(CHEMBL4217492)

IC50: 3.25E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455388(CHEMBL4205250)

IC50: 3.42E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455386(CHEMBL4213076)

IC50: 6.50E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455382(CHEMBL4210402)

IC50: 8.05E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455401(CHEMBL4210828)

IC50: 8.35E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455390(CHEMBL4206447)

IC50: 1.10E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455384(CHEMBL4206423)

IC50: 1.17E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455400(CHEMBL4212232)

IC50: 1.27E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455394(CHEMBL4208161)

IC50: 1.33E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455397(CHEMBL4217492)

IC50: 1.63E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455399(CHEMBL4205521)

IC50: 1.64E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455396(CHEMBL4211564)

IC50: 1.83E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455395(CHEMBL4204765)

IC50: 1.84E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455383(CHEMBL4215772)

IC50: 1.84E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455388(CHEMBL4205250)

IC50: 1.86E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455387(CHEMBL4209631)

IC50: 1.97E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455385(CHEMBL4216965)

IC50: 2.05E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455391(CHEMBL4215240)

IC50: 3.27E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455389(CHEMBL4216542)

IC50: 4.36E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455392(CHEMBL4203037)

IC50: >5.00E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455393(CHEMBL4207920)

IC50: >5.00E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455398(CHEMBL4203562)

IC50: >5.00E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455395(CHEMBL4204765)

IC50: 9.26E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455384(CHEMBL4206423)

IC50: >1.00E+5nMAssay Description:Inhibition of human PDE11AMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455384(CHEMBL4206423)

IC50: >1.00E+5nMAssay Description:Inhibition of human PDE9A2More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455384(CHEMBL4206423)

IC50: >1.00E+5nMAssay Description:Inhibition of human PDE6CMore data for this Ligand-Target Pair

UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455383(CHEMBL4215772)

IC50: >1.00E+5nMAssay Description:Inhibition of human PDE2AMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455383(CHEMBL4215772)

IC50: >1.00E+5nMAssay Description:Inhibition of human PDE10A2More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455383(CHEMBL4215772)

IC50: >1.00E+5nMAssay Description:Inhibition of human PDE9A2More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455383(CHEMBL4215772)

IC50: >1.00E+5nMAssay Description:Inhibition of human PDE7AMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455384(CHEMBL4206423)

IC50: >1.00E+5nMAssay Description:Inhibition of human PDE7AMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455383(CHEMBL4215772)

IC50: >1.00E+5nMAssay Description:Inhibition of human PDE6CMore data for this Ligand-Target Pair

UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455383(CHEMBL4215772)

IC50: >1.00E+5nMAssay Description:Inhibition of human PDE5AMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455383(CHEMBL4215772)

IC50: >1.00E+5nMAssay Description:Inhibition of human PDE3BMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

cGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455384(CHEMBL4206423)

IC50: >1.00E+5nMAssay Description:Inhibition of human PDE2AMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455384(CHEMBL4206423)

IC50: >1.00E+5nMAssay Description:Inhibition of human PDE1AMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455383(CHEMBL4215772)

IC50: >1.00E+5nMAssay Description:Inhibition of human PDE11AMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455384(CHEMBL4206423)

IC50: >1.00E+5nMAssay Description:Inhibition of human PDE8A1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
South China Agricultural University

Curated by ChEMBL

PNG

BDBM50455384(CHEMBL4206423)

IC50: >1.00E+5nMAssay Description:Inhibition of human PDE3BMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Displayed 1 to 50 (of 55 total ) | Next | Last >>

Filter my 55 hits

Targets 12▿
- cAMP-specific 3',5'-cyclic phosphodiesterase 4B 22
- cAMP-specific 3',5'-cyclic phosphodiesterase 4D 13
- High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A 2
- Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 2
- cGMP-specific 3',5'-cyclic phosphodiesterase 2
- cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B 2
- High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A 2
- Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' 2
- cGMP-dependent 3',5'-cyclic phosphodiesterase 2
- Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 2
- cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 2
- High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A 2
Publications 1▿
- Bioorg Med Chem Lett 28: 1188-1193 (2018) 55
Institutions 1▿
- South China Agricultural University 55
Affinity: 0.89 to 1.3E+5 nM▿
- IC50 55
- Affinity ≤ nM
Xtal structures: 2
Docked structures: 0
Catalog Cmpds: 2