BindingDB PrimarySearch_ki

Found 27 Enz. Inhib. hit(s) with all data for entry = 50002635

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)

IC50: <1nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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PDB

3D Structure (crystal)

Histone deacetylase 6(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50460794(CHEMBL4228653)

IC50: 8nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate after 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Heat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50008059(CHEBI:5292 | GELDANAMYCIN)

IC50: 16nMAssay Description:Inhibition of geldanamycin-based probe binding to HSP90 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

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KEGG PC cid PC sid PDB Similars

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3D Structure (crystal)

Histone deacetylase 6(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)

IC50: 20nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate after 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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CHEMBL DrugBank MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed DrugBank

Heat shock protein HSP 90-alpha(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50008059(CHEBI:5292 | GELDANAMYCIN)

IC50: 27nMAssay Description:Inhibition of HSP90alpha (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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KEGG PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Heat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50460795(CHEMBL4226547)

IC50: 110nMAssay Description:Inhibition of geldanamycin-based probe binding to HSP90 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

Details Article PubMed

Histone deacetylase 1(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)

IC50: 306nMAssay Description:Inhibition of HDAC1 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate after 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase ChEBI
CHEMBL DrugBank MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed DrugBank
PDB

3D Structure (crystal)

Heat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50460798(CHEMBL4227395)

IC50: 400nMAssay Description:Inhibition of geldanamycin-based probe binding to HSP90 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50460793(CHEMBL4225507)

IC50: 1.09E+3nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50460800(CHEMBL4228189)

IC50: 1.42E+3nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50460795(CHEMBL4226547)

IC50: 1.71E+3nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Histone deacetylase 1(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50460794(CHEMBL4228653)

IC50: 2.47E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate after 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Histone deacetylase 6(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50460796(CHEMBL4226814)

IC50: 2.82E+3nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate after 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50460798(CHEMBL4227395)

IC50: 3.45E+3nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50460799(CHEMBL4225827)

IC50: 3.76E+3nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Histone deacetylase 6(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50460799(CHEMBL4225827)

IC50: 6.30E+3nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate after 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50460797(CHEMBL4227007)

IC50: >1.00E+4nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Heat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50460797(CHEMBL4227007)

IC50: >1.00E+4nMAssay Description:Inhibition of geldanamycin-based probe binding to HSP90 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

Details Article PubMed

Heat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50460793(CHEMBL4225507)

IC50: >1.00E+4nMAssay Description:Inhibition of geldanamycin-based probe binding to HSP90 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

Details Article PubMed

Heat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50460800(CHEMBL4228189)

IC50: >1.00E+4nMAssay Description:Inhibition of geldanamycin-based probe binding to HSP90 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50460796(CHEMBL4226814)

IC50: 1.41E+4nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Heat shock protein HSP 90-alpha(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50460799(CHEMBL4225827)

IC50: 2.02E+4nMAssay Description:Inhibition of HSP90alpha (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50460794(CHEMBL4228653)

IC50: >1.00E+5nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Heat shock protein HSP 90-alpha(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50460794(CHEMBL4228653)

IC50: >1.00E+5nMAssay Description:Inhibition of HSP90alpha (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Histone deacetylase 1(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50460799(CHEMBL4225827)

IC50: >1.00E+5nMAssay Description:Inhibition of HDAC1 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate after 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Histone deacetylase 1(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50460796(CHEMBL4226814)

IC50: >1.00E+5nMAssay Description:Inhibition of HDAC1 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate after 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Heat shock protein HSP 90-alpha(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL

PNG

BDBM50460796(CHEMBL4226814)

IC50: >1.00E+5nMAssay Description:Inhibition of HSP90alpha (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed