Compile Data Set for Download or QSAR
Report error Found 74 Enz. Inhib. hit(s) with all data for entry = 50001186
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230355BDBM50230355(CHEMBL4061884)
Affinity DataKd:  180nMAssay Description:Binding affinity to PHGDH (unknown origin) by surface plasma resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 195606BDBM195606(NCT-503)
Affinity DataEC50:  2.30E+3nMAssay Description:Inhibition of PHGDH in human MDA-MB-468 cells assessed as decrease in serine fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 195606BDBM195606(NCT-503)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 195605BDBM195605(NCT-502 | US11225469, Compound 72)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271477BDBM50271477(CHEMBL4129748)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271521BDBM50271521(CHEMBL2140870)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 58473BDBM58473(N-(4-methylpyridin-2-yl)-4-[3-(trifluoromethyl)phe...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271523BDBM50271523(CHEMBL4129229 | US11225469, Compound 252)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271429BDBM50271429(CHEMBL4125702 | US11225469, Compound 294)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271412BDBM50271412(CHEMBL4125871 | US11225469, Compound 278)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232861BDBM50232861(CHEMBL2131647 | US11225469, Compound 24)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271461BDBM50271461(CHEMBL2143378 | US11225469, Compound 26)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271417BDBM50271417(CHEMBL4127018 | US11225469, Compound 250)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271438BDBM50271438(CHEMBL2137247 | US11225469, Compound 35)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271522BDBM50271522(CHEMBL4126002 | US11225469, Compound 251)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271425BDBM50271425(CHEMBL4126752)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271396BDBM50271396(CHEMBL4129360)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271418BDBM50271418(CHEMBL4128391 | US11225469, Compound 258)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271426BDBM50271426(CHEMBL4129099)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271427BDBM50271427(CHEMBL4127154 | US11225469, Compound 275)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271476BDBM50271476(CHEMBL4127403)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271415BDBM50271415(CHEMBL4125786 | US11225469, Compound 264)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271458BDBM50271458(CHEMBL3559789 | US11225469, Compound 30)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271434BDBM50271434(CHEMBL4128309 | US11225469, Compound 276)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271422BDBM50271422(CHEMBL4126183)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271398BDBM50271398(CHEMBL4126631 | US11225469, Compound 297)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271420BDBM50271420(CHEMBL4129623 | US11225469, Compound 266)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271405BDBM50271405(CHEMBL4125915 | US11225469, Compound 262)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271474BDBM50271474(CHEMBL2144036 | US11225469, Compound 34)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271410BDBM50271410(CHEMBL4127362 | US11225469, Compound 284)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271414BDBM50271414(CHEMBL4128834 | US11225469, Compound 296)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271419BDBM50271419(CHEMBL4128252 | US11225469, Compound 263)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271506BDBM50271506(CHEMBL2135778 | US11225469, Compound 116)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271416BDBM50271416(CHEMBL4127149)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271428BDBM50271428(CHEMBL4128967 | US11225469, Compound 298)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271462BDBM50271462(CHEMBL2132783 | US11225469, Compound 28)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271505BDBM50271505(CHEMBL4129706)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271459BDBM50271459(CHEMBL3125072 | US11225469, Compound 31)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 58473BDBM58473(N-(4-methylpyridin-2-yl)-4-[3-(trifluoromethyl)phe...)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271411BDBM50271411(CHEMBL4127255 | US11225469, Compound 280)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271421BDBM50271421(CHEMBL4129478)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271424BDBM50271424(CHEMBL4126359)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271403BDBM50271403(CHEMBL4129846)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271413BDBM50271413(CHEMBL4130136 | US11225469, Compound 281)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271435BDBM50271435(CHEMBL4126815 | US11225469, Compound 292)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 58473BDBM58473(N-(4-methylpyridin-2-yl)-4-[3-(trifluoromethyl)phe...)
Affinity DataIC50: 1.72E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 195605BDBM195605(NCT-502 | US11225469, Compound 72)
Affinity DataEC50:  1.75E+4nMAssay Description:Inhibition of PHGDH in human MDA-MB-468 cells assessed as decrease in serine fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271404BDBM50271404(CHEMBL4127244 | US11225469, Compound 265)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271400BDBM50271400(CHEMBL4130080 | US11225469, Compound 291)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271409BDBM50271409(CHEMBL4128755 | US11225469, Compound 289)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
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