Compile Data Set for Download or QSAR
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Found 13 Enz. Inhib. hit(s) with all data for entry = 50002063
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM21690(1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...)
Affinity DataIC50:  310nMAssay Description:Inhibition of Escherichia coli DNA gyrase A2B2 using relaxed pNO1 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452872(CHEMBL4210894)
Affinity DataIC50:  1.19E+3nMAssay Description:Inhibition of Escherichia coli DNA gyrase A2B2 using relaxed pNO1 as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452870(CHEMBL4203118)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Escherichia coli DNA gyrase A2B2 using relaxed pNO1 as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452869(CHEMBL4206009)
Affinity DataIC50:  6.35E+3nMAssay Description:Inhibition of Escherichia coli DNA gyrase A2B2 using relaxed pNO1 as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452870(CHEMBL4203118)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of CYP3A4-mediated testosterone metabolism in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452870(CHEMBL4203118)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of CYP3A4-mediated midazolam metabolism in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452871(CHEMBL4218256)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG transfected in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452872(CHEMBL4210894)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4-mediated testosterone metabolism in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452872(CHEMBL4210894)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4-mediated midazolam metabolism in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452870(CHEMBL4203118)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG transfected in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452871(CHEMBL4218256)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4-mediated testosterone metabolism in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452871(CHEMBL4218256)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4-mediated midazolam metabolism in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452872(CHEMBL4210894)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG transfected in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed