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Found 47 Enz. Inhib. hit(s) with all data for entry = 50001207
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272118(CHEMBL4130032)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272140(CHEMBL4128662)
Affinity DataIC50:  11nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272117(CHEMBL4126176)
Affinity DataIC50:  12nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272122(CHEMBL4129633)
Affinity DataIC50:  12nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272089(CHEMBL4126331)
Affinity DataIC50:  12nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272118(CHEMBL4130032)
Affinity DataIC50:  14nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272177(CHEMBL4127235)
Affinity DataIC50:  14nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272122(CHEMBL4129633)
Affinity DataIC50:  15nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272089(CHEMBL4126331)
Affinity DataIC50:  21nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272117(CHEMBL4126176)
Affinity DataIC50:  21nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272176(CHEMBL4128918)
Affinity DataIC50:  24nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272177(CHEMBL4127235)
Affinity DataIC50:  25nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272120(CHEMBL4128144)
Affinity DataIC50:  26nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272176(CHEMBL4128918)
Affinity DataIC50:  30nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272088(CHEMBL4126883)
Affinity DataIC50:  32nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272140(CHEMBL4128662)
Affinity DataIC50:  35nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272088(CHEMBL4126883)
Affinity DataIC50:  38nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272104(CHEMBL4126431)
Affinity DataIC50:  44nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272178(CHEMBL4128291)
Affinity DataIC50:  52nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272178(CHEMBL4128291)
Affinity DataIC50:  55nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272168(CHEMBL4129520)
Affinity DataIC50:  58nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272168(CHEMBL4129520)
Affinity DataIC50:  74nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272104(CHEMBL4126431)
Affinity DataIC50:  92nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272120(CHEMBL4128144)
Affinity DataIC50:  94nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272164(CHEMBL4128819)
Affinity DataIC50:  96nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272164(CHEMBL4128819)
Affinity DataIC50:  120nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272139(CHEMBL4126345)
Affinity DataIC50:  210nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272119(CHEMBL4130328)
Affinity DataIC50:  281nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272119(CHEMBL4130328)
Affinity DataIC50:  282nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272121(CHEMBL4130041)
Affinity DataIC50:  387nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272167(CHEMBL4127767)
Affinity DataIC50:  429nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272116(CHEMBL4129506)
Affinity DataIC50:  468nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272139(CHEMBL4126345)
Affinity DataIC50:  682nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272121(CHEMBL4130041)
Affinity DataIC50:  728nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272102(CHEMBL4128377)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272165(CHEMBL4129284)
Affinity DataIC50:  1.93E+3nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272102(CHEMBL4128377)
Affinity DataIC50:  3.76E+3nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272166(CHEMBL4129119)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272089(CHEMBL4126331)
Affinity DataIC50:  2.72E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272089(CHEMBL4126331)
Affinity DataIC50:  2.76E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272089(CHEMBL4126331)
Affinity DataIC50:  2.97E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272089(CHEMBL4126331)
Affinity DataIC50:  4.55E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272088(CHEMBL4126883)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human DGAT2 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272089(CHEMBL4126331)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human DGAT2 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272089(CHEMBL4126331)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272089(CHEMBL4126331)
Affinity DataEC50:  26nMAssay Description:Inhibition of DGAT1 in human HEK293 cells using [13C18]oleic acid as substrate assessed as decrease in triacylglycerol synthesis preincubated for 15 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50272088(CHEMBL4126883)
Affinity DataEC50:  20nMAssay Description:Inhibition of DGAT1 in human HEK293 cells using [13C18]oleic acid as substrate assessed as decrease in triacylglycerol synthesis preincubated for 15 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed