TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 660nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of mouse TRPC6More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair