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Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50001141
TargetSodium/glucose cotransporter 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50273462(CHEMBL4126863)
Affinity DataIC50:  0.630nMAssay Description:Inhibition of full-length human SGLT2 expressed in CHO cells assessed as decrease in [14C]-methyl alpha-D-glucopyranoside uptake after 1 hr by liquid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/glucose cotransporter 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50273463(CHEMBL4128909)
Affinity DataIC50:  0.810nMAssay Description:Inhibition of full-length human SGLT2 expressed in CHO cells assessed as decrease in [14C]-methyl alpha-D-glucopyranoside uptake after 1 hr by liquid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/glucose cotransporter 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50273460(CHEMBL4128089)
Affinity DataIC50:  1nMAssay Description:Inhibition of full-length human SGLT2 expressed in CHO cells assessed as decrease in [14C]-methyl alpha-D-glucopyranoside uptake after 1 hr by liquid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/glucose cotransporter 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM20880((2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)me...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of full-length human SGLT2 expressed in CHO cells assessed as decrease in [14C]-methyl alpha-D-glucopyranoside uptake after 1 hr by liquid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetSodium/glucose cotransporter 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50273461(CHEMBL4130121)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of full-length human SGLT2 expressed in CHO cells assessed as decrease in [14C]-methyl alpha-D-glucopyranoside uptake after 1 hr by liquid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/glucose cotransporter 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50273459(CHEMBL4127858)
Affinity DataIC50:  12nMAssay Description:Inhibition of full-length human SGLT2 expressed in CHO cells assessed as decrease in [14C]-methyl alpha-D-glucopyranoside uptake after 1 hr by liquid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed