Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50001141
TargetSodium/glucose cotransporter 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50273462(CHEMBL4126863)
Affinity DataIC50: 0.630nMAssay Description:Inhibition of full-length human SGLT2 expressed in CHO cells assessed as decrease in [14C]-methyl alpha-D-glucopyranoside uptake after 1 hr by liquid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50273463(CHEMBL4128909)
Affinity DataIC50: 0.810nMAssay Description:Inhibition of full-length human SGLT2 expressed in CHO cells assessed as decrease in [14C]-methyl alpha-D-glucopyranoside uptake after 1 hr by liquid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50273460(CHEMBL4128089)
Affinity DataIC50: 1nMAssay Description:Inhibition of full-length human SGLT2 expressed in CHO cells assessed as decrease in [14C]-methyl alpha-D-glucopyranoside uptake after 1 hr by liquid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50273461(CHEMBL4130121)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of full-length human SGLT2 expressed in CHO cells assessed as decrease in [14C]-methyl alpha-D-glucopyranoside uptake after 1 hr by liquid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of full-length human SGLT2 expressed in CHO cells assessed as decrease in [14C]-methyl alpha-D-glucopyranoside uptake after 1 hr by liquid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50273459(CHEMBL4127858)
Affinity DataIC50: 12nMAssay Description:Inhibition of full-length human SGLT2 expressed in CHO cells assessed as decrease in [14C]-methyl alpha-D-glucopyranoside uptake after 1 hr by liquid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2020
Entry Details Article
PubMed