Compile Data Set for Download or QSAR
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Report error Found 85 Enz. Inhib. hit(s) with all data for entry = 50001222
TargetLysine-specific demethylase 5A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273478(CHEMBL4130224)
Affinity DataKi:  7.40E+4nMAssay Description:Mixed type inhibition of KDM5A (L88 to G353 residues) ARID/PHD1/2/3 deletion mutant (unknown origin) demethylation activity using H3(1-21)K4me3 pepti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 5A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM223320(KDOAM-25)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of KDM5A (M1 to L801 residues) PHD2/3 deletion mutant (unknown origin) demethylation activity preincubated for 10 mins followed by peptide...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHistone lysine demethylase PHF8(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273472(CHEMBL4126235)
Affinity DataIC50:  1.70E+3nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7B (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 5A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM223320(KDOAM-25)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of KDM5A (M1 to L801 residues) PHD2/3 deletion mutant (unknown origin) demethylation activity preincubated for 10 mins followed by peptide...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetLysine-specific demethylase 7A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273472(CHEMBL4126235)
Affinity DataIC50:  1.90E+3nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase PHF2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273472(CHEMBL4126235)
Affinity DataIC50:  2.70E+3nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7C (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 7A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273469(CHEMBL4126406)
Affinity DataIC50:  5.60E+3nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 7A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273469(CHEMBL4126406)
Affinity DataIC50:  5.60E+3nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 5A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50270477(CHEMBL4127210)
Affinity DataIC50:  1.26E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from recombinant His6-tagged human KDM5A (PHD3) (1542 to 1660 residues) ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 5A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM92787(WAG-003)
Affinity DataIC50:  3.00E+4nMAssay Description:Displacement of H3K4me3 binding to Halo-tagged GST-fused KDM5A PHD3 domain (unknown origin) expressed in Escherichia coli by HaloTag-based peptide di...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 5A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273478(CHEMBL4130224)
Affinity DataIC50:  3.70E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from recombinant His6-tagged human KDM5A (PHD3) (1542 to 1660 residues) ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 5A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM92788(WAG-005)
Affinity DataIC50:  4.10E+4nMAssay Description:Displacement of H3K4me3 binding to Halo-tagged GST-fused KDM5A PHD3 domain (unknown origin) expressed in Escherichia coli by HaloTag-based peptide di...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 7A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM92788(WAG-005)
Affinity DataIC50:  5.00E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 7A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM92788(WAG-005)
Affinity DataIC50:  5.00E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 7A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273477(CHEMBL4129830)
Affinity DataIC50:  6.80E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 7A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273474(CHEMBL4129980)
Affinity DataIC50:  7.60E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 5A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273478(CHEMBL4130224)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of KDM5A (M1 to L801 residues) PHD2/3 deletion mutant (unknown origin) demethylation activity preincubated for 10 mins followed by peptide...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 5A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM92788(WAG-005)
Affinity DataIC50:  8.20E+4nMAssay Description:Inhibition of KDM5A (M1 to L801 residues) PHD2/3 deletion mutant (unknown origin) demethylation activity preincubated for 10 mins followed by peptide...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 5A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM92788(WAG-005)
Affinity DataIC50:  8.20E+4nMAssay Description:Inhibition of KDM5A (M1 to L801 residues) PHD2/3 deletion mutant (unknown origin) demethylation activity preincubated for 10 mins followed by peptide...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase PHF2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM18957((2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-di...)
Affinity DataIC50:  8.40E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7C (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 7A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273478(CHEMBL4130224)
Affinity DataIC50:  8.60E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 7A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273478(CHEMBL4130224)
Affinity DataIC50:  8.60E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 7A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273476(CHEMBL4128152)
Affinity DataIC50:  9.80E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 7A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273476(CHEMBL4128152)
Affinity DataIC50:  9.80E+4nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 5A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM18957((2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-di...)
Affinity DataIC50:  9.90E+4nMAssay Description:Inhibition of KDM5A (M1 to L801 residues) PHD2/3 deletion mutant (unknown origin) demethylation activity preincubated for 10 mins followed by peptide...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 7A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50270479(CHEMBL4127094)
Affinity DataIC50:  1.02E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 7A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273473(CHEMBL4127792)
Affinity DataIC50:  1.04E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone lysine demethylase PHF8(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273478(CHEMBL4130224)
Affinity DataIC50:  1.20E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7B (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone lysine demethylase PHF8(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273469(CHEMBL4126406)
Affinity DataIC50:  1.26E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7B (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 7A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273471(CHEMBL4127515)
Affinity DataIC50:  1.51E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 7A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM18957((2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-di...)
Affinity DataIC50:  1.56E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 7A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM18957((2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-di...)
Affinity DataIC50:  1.56E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase PHF2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273475(CHEMBL4126951)
Affinity DataIC50:  1.58E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7C (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 5A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273475(CHEMBL4126951)
Affinity DataIC50:  1.66E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from recombinant His6-tagged human KDM5A (PHD3) (1542 to 1660 residues) ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 5A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50270475(CHEMBL4126135)
Affinity DataIC50:  1.98E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from recombinant His6-tagged human KDM5A (PHD3) (1542 to 1660 residues) ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 5A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273477(CHEMBL4129830)
Affinity DataIC50:  1.98E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from recombinant His6-tagged human KDM5A (PHD3) (1542 to 1660 residues) ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 5A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273472(CHEMBL4126235)
Affinity DataIC50:  2.18E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from recombinant His6-tagged human KDM5A (PHD3) (1542 to 1660 residues) ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase PHF2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273477(CHEMBL4129830)
Affinity DataIC50:  2.20E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7C (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone lysine demethylase PHF8(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273471(CHEMBL4127515)
Affinity DataIC50:  2.21E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7B (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 5A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273474(CHEMBL4129980)
Affinity DataIC50:  2.23E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from recombinant His6-tagged human KDM5A (PHD3) (1542 to 1660 residues) ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase PHF2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273474(CHEMBL4129980)
Affinity DataIC50:  2.28E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7C (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone lysine demethylase PHF8(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273474(CHEMBL4129980)
Affinity DataIC50:  2.40E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7B (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone lysine demethylase PHF8(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273477(CHEMBL4129830)
Affinity DataIC50:  2.42E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7B (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone lysine demethylase PHF8(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM18957((2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-di...)
Affinity DataIC50:  2.52E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7B (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone lysine demethylase PHF8(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273470(CHEMBL4128613)
Affinity DataIC50:  2.86E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7B (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 7A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273475(CHEMBL4126951)
Affinity DataIC50:  2.95E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone lysine demethylase PHF8(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273476(CHEMBL4128152)
Affinity DataIC50: >3.00E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7B (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone lysine demethylase PHF8(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM92787(WAG-003)
Affinity DataIC50:  3.07E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7B (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone lysine demethylase PHF8(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273469(CHEMBL4126406)
Affinity DataIC50:  3.10E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7B (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 5A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50273471(CHEMBL4127515)
Affinity DataIC50:  3.14E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from recombinant His6-tagged human KDM5A (PHD3) (1542 to 1660 residues) ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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