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Found 11 Enz. Inhib. hit(s) with all data for entry = 50001267
TargetGenome polyprotein(Dengue virus)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50274119(CHEMBL4126343)
Affinity DataIC50:  340nMAssay Description:Inhibition of Dengue virus 4 NS5 full length RdRp activity using RNA as template assessed as inhibition of NTPs incorporation after 90 mins by FAPA a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50274120(CHEMBL3417270)
Affinity DataIC50:  360nMAssay Description:Inhibition of Dengue virus 2 NS5 full length RdRp activity using RNA as template/primer assessed as inhibition of [alpha3P]GTP incorporation by SDS-P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50274124(CHEMBL4125966 | US10793591, Compound 12)
Affinity DataIC50:  650nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50274121(CHEMBL4127092)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50274122(CHEMBL4127819)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50274125(CHEMBL4127565)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50274118(CHEMBL4127030 | US10793591, Compound 7a)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50274117(CHEMBL4127921)
Affinity DataIC50:  1.59E+4nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50274123(CHEMBL4129313)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed