Compile Data Set for Download or QSAR
maximum 50k data
Found 19 Enz. Inhib. hit(s) with all data for entry = 50001859
TargetToll-like receptor 4(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50412172(CHEMBL4169865)
Affinity DataIC50:  1.24E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50408537(CHEMBL4175471)
Affinity DataIC50:  1.25E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50411356(CHEMBL4163980)
Affinity DataIC50:  1.36E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50410089(CHEMBL4175587)
Affinity DataIC50:  1.51E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50408989(CHEMBL4168989)
Affinity DataIC50:  1.67E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50413049(CHEMBL4171849)
Affinity DataIC50:  2.11E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50412113(CHEMBL4161940)
Affinity DataIC50:  2.17E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50408536(CHEMBL4171608)
Affinity DataIC50:  2.47E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50408993(CHEMBL4164834)
Affinity DataIC50:  2.59E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50408973(CHEMBL4174733)
Affinity DataIC50:  2.60E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50413050(CHEMBL4168489)
Affinity DataIC50:  2.85E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50410820(CHEMBL4176208)
Affinity DataIC50:  3.15E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM25759(CHEMBL723 | Carvedilol | Coreg | Dilatrend | Eucar...)
Affinity DataIC50:  3.22E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50411862(CHEMBL2440787)
Affinity DataIC50:  3.26E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50351547(CHEMBL1223751)
Affinity DataIC50:  3.42E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50408538(CHEMBL4174322)
Affinity DataIC50:  3.46E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50408964(CHEMBL4163298)
Affinity DataIC50:  5.15E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50408991(CHEMBL4167187)
Affinity DataIC50:  5.46E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50408961(CHEMBL4170576)
Affinity DataIC50:  5.54E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed