Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50001859
TargetToll-like receptor 4(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50412172(CHEMBL4169865)
Affinity DataIC50: 1.24E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50408537(CHEMBL4175471)
Affinity DataIC50: 1.25E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50411356(CHEMBL4163980)
Affinity DataIC50: 1.36E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50410089(CHEMBL4175587)
Affinity DataIC50: 1.51E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50408989(CHEMBL4168989)
Affinity DataIC50: 1.67E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50413049(CHEMBL4171849)
Affinity DataIC50: 2.11E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50412113(CHEMBL4161940)
Affinity DataIC50: 2.17E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50408536(CHEMBL4171608)
Affinity DataIC50: 2.47E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50408993(CHEMBL4164834)
Affinity DataIC50: 2.59E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50408973(CHEMBL4174733)
Affinity DataIC50: 2.60E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50413050(CHEMBL4168489)
Affinity DataIC50: 2.85E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50410820(CHEMBL4176208)
Affinity DataIC50: 3.15E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM25759([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...)
Affinity DataIC50: 3.22E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50411862(CHEMBL2440787)
Affinity DataIC50: 3.26E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50351547(CHEMBL1223751)
Affinity DataIC50: 3.42E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50408538(CHEMBL4174322)
Affinity DataIC50: 3.46E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50408964(CHEMBL4163298)
Affinity DataIC50: 5.15E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50408991(CHEMBL4167187)
Affinity DataIC50: 5.46E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50408961(CHEMBL4170576)
Affinity DataIC50: 5.54E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed