Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50008585
TargetDNA topoisomerase 2-beta(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520631BDBM50520631(Ametantrone)
Affinity DataIC50: 30nMAssay Description:Poison activity at recombinant human topoisomerase 2beta using pBR322 plasmid as substrate after 30 mins by ethidium bromide staining based agarose g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-beta(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520632BDBM50520632(CHEMBL4553471)
Affinity DataIC50: 1.06E+3nMAssay Description:Poison activity at recombinant human topoisomerase 2beta using pBR322 plasmid as substrate after 30 mins by ethidium bromide staining based agarose g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-beta(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520634BDBM50520634(CHEMBL4575796)
Affinity DataIC50: 1.15E+3nMAssay Description:Poison activity at recombinant human topoisomerase 2beta using pBR322 plasmid as substrate after 30 mins by ethidium bromide staining based agarose g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-beta(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520633BDBM50520633(CHEMBL4448353)
Affinity DataIC50: 4.34E+3nMAssay Description:Poison activity at recombinant human topoisomerase 2beta using pBR322 plasmid as substrate after 30 mins by ethidium bromide staining based agarose g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-beta(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520636BDBM50520636(CHEMBL4467805)
Affinity DataIC50: 5.25E+3nMAssay Description:Poison activity at recombinant human topoisomerase 2beta using pBR322 plasmid as substrate after 30 mins by ethidium bromide staining based agarose g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127140BDBM50127140(4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylid...)
Affinity DataIC50: 3.38E+4nMAssay Description:Inhibition of recombinant human topoisomerase 2alpha using supercoiled pNO1 plasmid as substrate after 30 mins by SYBR-GOLD staining based fluorimetr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-alpha(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50362243BDBM50362243(CHEMBL1939412)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of recombinant human topoisomerase 2alpha using supercoiled pNO1 plasmid as substrate after 30 mins by SYBR-GOLD staining based fluorimetr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520635BDBM50520635(CHEMBL4435344)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of recombinant human topoisomerase 2alpha using supercoiled pNO1 plasmid as substrate after 30 mins by SYBR-GOLD staining based fluorimetr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed