Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50001743
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50361164(CHEMBL4174188)
Affinity DataIC50: 13nMAssay Description:Inhibition of rhodamine-tagged FP probe binding to NOTUM in human SW620 cells conditioned media pretreated for 30 mins followed by rhodamine-tagged F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50361164(CHEMBL4174188)
Affinity DataIC50: 89nMAssay Description:Inhibition of NOTUM in human SW620 cells conditioned medium assessed as preservation of Wnt3A activity pretreated for 1 hr followed by Wnt3A producin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50361169(CHEMBL4163486)
Affinity DataIC50: 200nMAssay Description:Inhibition of rhodamine-tagged FP probe binding to NOTUM in human SW620 cells conditioned media pretreated for 30 mins followed by rhodamine-tagged F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50361168(CHEMBL4160119)
Affinity DataIC50: 290nMAssay Description:Inhibition of rhodamine-tagged FP probe binding to NOTUM in human SW620 cells conditioned media pretreated for 30 mins followed by rhodamine-tagged F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50361165(CHEMBL4170569)
Affinity DataIC50: 677nMAssay Description:Inhibition of rhodamine-tagged FP probe binding to recombinant human C-terminal FLAG-tagged NOTUM expressed in HEK293T cells pretreated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50361167(CHEMBL4159918)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of rhodamine-tagged FP probe binding to recombinant human C-terminal FLAG-tagged NOTUM expressed in HEK293T cells pretreated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50361166(CHEMBL4171791)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of NOTUM in human SW620 cells conditioned medium assessed as preservation of Wnt3A activity pretreated for 1 hr followed by Wnt3A producin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50361163(CHEMBL4170762)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rhodamine-tagged FP probe binding to NOTUM in human SW620 cells conditioned media pretreated for 30 mins followed by rhodamine-tagged F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50361166(CHEMBL4171791)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rhodamine-tagged FP probe binding to NOTUM in human SW620 cells conditioned media pretreated for 30 mins followed by rhodamine-tagged F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed