Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50002777
TargetProstaglandin G/H synthase 1(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462860BDBM50462860(CHEMBL4241735)
Affinity DataIC50: 40nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11639BDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 51nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17638BDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462860BDBM50462860(CHEMBL4241735)
Affinity DataIC50: 100nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022271BDBM50022271(2-(3-benzoylphenyl)propanoic acid | 2-(3-Benzoylph...)
Affinity DataIC50: 110nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326534BDBM50326534(furan-3-yl(4-(methylsulfonyl)phenyl)methanone | CH...)
Affinity DataIC50: 180nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022271BDBM50022271(2-(3-benzoylphenyl)propanoic acid | 2-(3-Benzoylph...)
Affinity DataIC50: 180nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462866BDBM50462866(CHEMBL4238821)
Affinity DataIC50: 280nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462863BDBM50462863(CHEMBL4247064)
Affinity DataIC50: 390nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326534BDBM50326534(furan-3-yl(4-(methylsulfonyl)phenyl)methanone | CH...)
Affinity DataIC50: 710nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462863BDBM50462863(CHEMBL4247064)
Affinity DataIC50: 760nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17638BDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 900nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462861BDBM50462861(CHEMBL4248484)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009859BDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462861BDBM50462861(CHEMBL4248484)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 54705BDBM54705(calcium;2-(3-phenoxyphenyl)propanoic acid;hydrate ...)
Affinity DataIC50: 2.73E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009859BDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 3.35E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339185BDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)
Affinity DataIC50: 3.36E+3nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462866BDBM50462866(CHEMBL4238821)
Affinity DataIC50: 4.89E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462862BDBM50462862(CHEMBL4243293)
Affinity DataIC50: 5.29E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462865BDBM50462865(CHEBI:31838 | Metiazinic Acid | RP-16091)
Affinity DataIC50: 6.23E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462864BDBM50462864(CHEMBL4242712)
Affinity DataIC50: 7.02E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11639BDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462865BDBM50462865(CHEBI:31838 | Metiazinic Acid | RP-16091)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339185BDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462862BDBM50462862(CHEMBL4243293)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462864BDBM50462864(CHEMBL4242712)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Universitat De Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 54705BDBM54705(calcium;2-(3-phenoxyphenyl)propanoic acid;hydrate ...)
Affinity DataIC50: 2.63E+4nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed