Found 24 Enz. Inhib. hit(s) with all data for entry = 50001499 
Affinity DataIC50: 0.600nMAssay Description:Inverse agonist activity at human His6-tagged RORgammat LBD (264 to 518 residues) assessed as reduction in biotinylated RIP140 co-activator recruitme...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 3.10nMAssay Description:Inverse agonist activity at human His6-tagged RORgammat LBD (264 to 518 residues) assessed as reduction in biotinylated RIP140 co-activator recruitme...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inverse agonist activity at human full-length eGFP-tagged RORgammat expressed in human HUT78 T-cells assessed as inhibition of PMA/CD3 monoclonal ant...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inverse agonist activity at human GAL4-DBD fused RORgammat LBD expressed in human Jurkat cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inverse agonist activity at human His6-tagged RORgammat LBD (264 to 518 residues) assessed as reduction in biotinylated RIP140 co-activator recruitme...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inverse agonist activity at RORgammat in human PBMC-derived CD4-positive Th-17 polarized cells assessed as reduction in IL4/anti-IFN-gamma antibody-s...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inverse agonist activity at human His6-tagged RORgammat LBD (264 to 518 residues) assessed as reduction in biotinylated RIP140 co-activator recruitme...More data for this Ligand-Target Pair
Affinity DataIC50: 255nMAssay Description:Inverse agonist activity at RORgammat in human whole blood assessed as reduction in Con A/IL-23-stimulated IL-17 secretion after 72 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 770nMAssay Description:Binding affinity to His-zz-tagged RORgammat (unknown origin) after 45 mins by MS reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+3nMAssay Description:Inverse agonist activity at human His6-tagged RORgammat LBD (264 to 518 residues) assessed as reduction in biotinylated RIP140 co-activator recruitme...More data for this Ligand-Target Pair
Affinity DataIC50: 4.11E+3nMAssay Description:Inverse agonist activity at human GAL4-DBD fused RORbeta LBD expressed in human Jurkat cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.73E+3nMAssay Description:Inverse agonist activity at human His6-tagged RORgammat LBD (264 to 518 residues) assessed as reduction in biotinylated RIP140 co-activator recruitme...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Binding affinity to His-zz-tagged RORgammat (unknown origin) after 45 mins by MS reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Binding affinity to His-zz-tagged RORgammat (unknown origin) after 45 mins by MS reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inverse agonist activity at human His6-tagged RORgammat LBD (264 to 518 residues) assessed as reduction in biotinylated RIP140 co-activator recruitme...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inverse agonist activity at human GAL4-DBD fused RORalpha LBD expressed in human Jurkat cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Binding affinity to His-zz-tagged RORgammat (unknown origin) after 45 mins by MS reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Binding affinity to His-zz-tagged RORgammat (unknown origin) after 45 mins by MS reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.90E+4nMAssay Description:Binding affinity to His-zz-tagged RORgammat (unknown origin) after 45 mins by MS reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.16E+5nMAssay Description:Binding affinity to His-zz-tagged RORgammat (unknown origin) after 45 mins by MS reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMAssay Description:Binding affinity to His-zz-tagged RORgammat (unknown origin) after 45 mins by MS reporter assayMore data for this Ligand-Target Pair
Affinity DataKd: 8nMAssay Description:Binding affinity to RORgammat (unknown origin) by ITCMore data for this Ligand-Target Pair
Affinity DataKd: 36nMAssay Description:Binding affinity to RORgammat (unknown origin) by reporter displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 465nMAssay Description:Binding affinity to RORgammat (unknown origin) by reporter displacement assayMore data for this Ligand-Target Pair
