Compile Data Set for Download or QSAR
Report error Found 86 Enz. Inhib. hit(s) with all data for entry = 50002454
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458677(CHEMBL4212084)
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at human CRTh2 expressed in HEK cells assessed as inhibition of DK-PGD2-mediated attenuation of forskolin-induced intracellular c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458673(CHEMBL4207731)
Affinity DataIC50: 0.900nMAssay Description:Antagonist activity at human CRTh2 expressed in HEK cells assessed as inhibition of DK-PGD2-mediated attenuation of forskolin-induced intracellular c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458677(CHEMBL4212084)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at human CRTh2 expressed in CHOK1 cells assessed as inhibition of PGD2-induced beta-arrestin recruitment incubated for 30 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458673(CHEMBL4207731)
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at human CRTh2 expressed in CHOK1 cells assessed as inhibition of PGD2-induced beta-arrestin recruitment incubated for 30 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458652(CHEMBL4202859)
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at human CRTh2 expressed in CHOK1 cells assessed as inhibition of PGD2-induced beta-arrestin recruitment incubated for 30 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458667(CHEMBL4207935)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at human CRTh2 expressed in CHOK1 cells assessed as inhibition of PGD2-induced beta-arrestin recruitment incubated for 30 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458652(CHEMBL4202859)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human CRTh2 expressed in HEK cells assessed as inhibition of DK-PGD2-mediated attenuation of forskolin-induced intracellular c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458670(CHEMBL4212838)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458690(CHEMBL4205047)
Affinity DataIC50: 2.40nMAssay Description:Antagonist activity at human CRTh2 expressed in CHOK1 cells assessed as inhibition of PGD2-induced beta-arrestin recruitment incubated for 30 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458673(CHEMBL4207731)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458667(CHEMBL4207935)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458666(CHEMBL4204359)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458672(CHEMBL4203572)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458652(CHEMBL4202859)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458663(CHEMBL4208457)
Affinity DataIC50: 3.5nMAssay Description:Antagonist activity at human CRTh2 expressed in CHOK1 cells assessed as inhibition of PGD2-induced beta-arrestin recruitment incubated for 30 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458652(CHEMBL4202859)
Affinity DataIC50: 3.60nMAssay Description:Antagonist activity at CRTh2 in human whole blood assessed as inhibition of DK-PGD2-induced eosinophils shape change preincubated for 10 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458681(CHEMBL4215576)
Affinity DataIC50: 3.90nMAssay Description:Antagonist activity at CRTh2 in human whole blood assessed as inhibition of DK-PGD2-induced eosinophils shape change preincubated for 10 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458667(CHEMBL4207935)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human CRTh2 expressed in HEK cells assessed as inhibition of DK-PGD2-mediated attenuation of forskolin-induced intracellular c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458681(CHEMBL4215576)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458677(CHEMBL4212084)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458663(CHEMBL4208457)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458669(CHEMBL4215049)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458688(CHEMBL4213245)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458667(CHEMBL4207935)
Affinity DataIC50: 6.20nMAssay Description:Antagonist activity at CRTh2 in human whole blood assessed as inhibition of DK-PGD2-induced eosinophils shape change preincubated for 10 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458672(CHEMBL4203572)
Affinity DataIC50: 6.20nMAssay Description:Antagonist activity at CRTh2 in human whole blood assessed as inhibition of DK-PGD2-induced eosinophils shape change preincubated for 10 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458681(CHEMBL4215576)
Affinity DataIC50: 7nMAssay Description:Antagonist activity at human CRTh2 expressed in HEK cells assessed as inhibition of DK-PGD2-mediated attenuation of forskolin-induced intracellular c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458683(CHEMBL4203786)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458671(CHEMBL4210620)
Affinity DataKi:  7.30nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458663(CHEMBL4208457)
Affinity DataIC50: 7.90nMAssay Description:Antagonist activity at CRTh2 in human whole blood assessed as inhibition of DK-PGD2-induced eosinophils shape change preincubated for 10 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458663(CHEMBL4208457)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at human CRTh2 expressed in HEK cells assessed as inhibition of DK-PGD2-mediated attenuation of forskolin-induced intracellular c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458659(CHEMBL4203383)
Affinity DataKi:  8.10nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458673(CHEMBL4207731)
Affinity DataIC50: 8.20nMAssay Description:Antagonist activity at CRTh2 in human whole blood assessed as inhibition of DK-PGD2-induced eosinophils shape change preincubated for 10 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458690(CHEMBL4205047)
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458684(CHEMBL4203284)
Affinity DataKi:  8.60nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458671(CHEMBL4210620)
Affinity DataIC50: 8.90nMAssay Description:Antagonist activity at CRTh2 in human whole blood assessed as inhibition of DK-PGD2-induced eosinophils shape change preincubated for 10 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458674(CHEMBL4212522)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458659(CHEMBL4203383)
Affinity DataIC50: 9.30nMAssay Description:Antagonist activity at human CRTh2 expressed in CHOK1 cells assessed as inhibition of PGD2-induced beta-arrestin recruitment incubated for 30 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458680(CHEMBL4205802)
Affinity DataKi:  9.40nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458668(CHEMBL4217503)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458690(CHEMBL4205047)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human CRTh2 expressed in HEK cells assessed as inhibition of DK-PGD2-mediated attenuation of forskolin-induced intracellular c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458671(CHEMBL4210620)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human CRTh2 expressed in CHOK1 cells assessed as inhibition of PGD2-induced beta-arrestin recruitment incubated for 30 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458657(CHEMBL4216012)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458655(CHEMBL4207377)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human CRTh2 expressed in HEK cells assessed as forskolin-induced intracellular cAMP accumulation by ELISA based chemiluminescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458675(CHEMBL4207202)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458672(CHEMBL4203572)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human CRTh2 expressed in CHOK1 cells assessed as inhibition of PGD2-induced beta-arrestin recruitment incubated for 30 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458677(CHEMBL4212084)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at CRTh2 in human whole blood assessed as inhibition of DK-PGD2-induced eosinophils shape change preincubated for 10 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458687(CHEMBL4208314)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458659(CHEMBL4203383)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at CRTh2 in human whole blood assessed as inhibition of DK-PGD2-induced eosinophils shape change preincubated for 10 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458664(CHEMBL4216735)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50458682(CHEMBL4211054)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
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